{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:47:41Z","timestamp":1771019261548,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T00:00:00Z","timestamp":1575849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["APQ\u201003422.12\u201015"],"award-info":[{"award-number":["APQ\u201003422.12\u201015"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Norovirus (NoV) is currently the leading cause of nonbacterial gastroenteritis. In Brazil, few studies have characterized the molecular, epidemiological and clinical features of NoV\u2010associated gastroenteritis. This study aimed to describe the molecular and clinicoepidemiological findings of NoV infections in patients of all ages throughout Pernambuco state, Northeast Brazil. Thus, 1135 stool samples were analyzed from patients with gastroenteritis from Pernambuco state. NoV was detected by enzyme immunoassay in 125 (11.01%) samples. Regarding gender distribution, 55 (44.00%) patients were female and 70 (56.00%) male. Their ages ranged from 5 days to 87 years, and the group most affected by NoV infection (88.00%) was children under 3 years. Complete clinical information was available for 88 out of 125 NoV\u2010positive patients. Diarrhea was present in all patients and vomiting was reported in 60 patients (68.68%). Nine patients (10.22%) had bloody stools and 46 (52.27%) had a fever, with temperatures ranging from 37.90\u00b0C to 39.90\u00b0C (mean 38.20\u00b0C). NoV was detected mainly in the summer\u2010autumn seasons. Genome sequencing and phylogenetic analyses identified four different NoV GII genotypes circulating in this area of the country. Therefore, our study provided valuable information about the clinics and epidemiology of NoV infection in tropical settings and will assist health authorities to develop better control strategies against this important pathogen.<\/jats:p>","DOI":"10.1002\/jmv.25631","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T18:53:10Z","timestamp":1574189590000},"page":"1093-1101","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Norovirus\u2010associated gastroenteritis, Pernambuco, Northeast Brazil, 2014\u20102017"],"prefix":"10.1002","volume":"92","author":[{"given":"Klarissa M.","family":"Guarines","sequence":"first","affiliation":[{"name":"Department of Virology, Aggeu Magalh\u00e3es Institute (IAM) Oswaldo Cruz Foundation (Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata P. 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