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Mask\u2010wearing and handwashing can slow the spread of the virus, but currently, masks are in shortage in many countries, and timely handwashing is often impossible. In this study, the efficacy of three types of masks and instant hand wiping was evaluated using the avian influenza virus to mock the coronavirus. Virus quantification was performed using real\u2010time reverse transcription\u2010polymerase chain reaction. Previous studies on mask\u2010wearing were reviewed. The results showed that instant hand wiping using a wet towel soaked in water containing 1.00% soap powder, 0.05% active chlorine, or 0.25% active chlorine from sodium hypochlorite removed 98.36%, 96.62%, and 99.98% of the virus from hands, respectively. N95 masks, medical masks, and homemade masks made of four\u2010layer kitchen paper and one\u2010layer cloth could block 99.98%, 97.14%, and 95.15% of the virus in aerosols. Medical mask\u2010wearing which was supported by many studies was opposed by other studies possibly due to erroneous judgment. With these data, we propose the approach of mask\u2010wearing plus instant hand hygiene (MIH) to slow the exponential spread of the virus. This MIH approach has been supported by the experiences of seven countries in fighting against COVID\u201019. Collectively, a simple approach to slow the exponential spread of SARS\u2010CoV\u20102 was proposed with the support of experiments, literature review, and control experiences.<\/jats:p>","DOI":"10.1002\/jmv.25805","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T09:14:25Z","timestamp":1585646065000},"page":"1567-1571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":237,"title":["Potential utilities of mask\u2010wearing and instant hand hygiene for fighting SARS\u2010CoV\u20102"],"prefix":"10.1002","volume":"92","author":[{"given":"Qing\u2010Xia","family":"Ma","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Shan","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010Liang","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui\u2010Mei","family":"Li","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui\u2010Mei","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0404-0830","authenticated-orcid":false,"given":"Ji\u2010Ming","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Qingdao Agricultural University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"e_1_2_10_3_1","unstructured":"Chinese National Health Commission (NHC). 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