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A handful\u00a0pieces\u00a0of literature have summarized its clinical and radiologic features, whereas therapies for COVID\u201019 are rather limited. To evaluate the efficacy of convalescent plasma therapy in COVID\u201019 patients, we did this timely descriptive study. Six laboratory\u2010confirmed COVID\u201019 patients were enrolled and received the transfusion of ABO\u2010compatible convalescent plasma. The efficacy of this intervention was determined by the alleviation of symptoms, changes in radiologic abnormalities and laboratory tests. No obvious adverse effect observed during the treatment. Transfusion of convalescent plasma led to a resolution of ground\u2010glass opacities and consolidation in patients #1, #2, #3, #4, and #6. In patients #1 and #5 who presented with SARS\u2010CoV\u20102 in throat swab, convalescent plasma therapy elicited an elimination of the virus. Serologic analysis indicated an immediate increase in anti\u2010SARS\u2010CoV\u20102 antibody titers in patients #2 and #3, but not in patient #1. This study indicates that convalescent plasma therapy is effective and specific for COVID\u201019. This intervention has a special significance for eliminating SARS\u2010CoV\u20102 and is believed to be a promising state\u2010of\u2010the\u2010art therapy during COVID\u201019 pandemic crisis.<\/jats:p>","DOI":"10.1002\/jmv.25882","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T15:54:09Z","timestamp":1586966049000},"page":"1890-1901","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":303,"title":["Treatment with convalescent plasma for COVID\u201019 patients in Wuhan, China"],"prefix":"10.1002","volume":"92","author":[{"given":"Mingxiang","family":"Ye","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Jinling Hospital Nanjing University School of Medicine  Nanjing China"},{"name":"Department of Infectious Disease, Unit 4\u20101 Wuhan Huoshenshan Hospital  Wuhan 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