{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:00:51Z","timestamp":1793642451821,"version":"4.5.1"},"reference-count":49,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T00:00:00Z","timestamp":1593388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In Pakistan, the burden of influenza was largely unknown, as no formal surveillance system was in place. In 2008, an influenza surveillance system was set up in eight sentinel sites. This study describes the epidemiology of influenza virus using a 10\u2010year surveillance data from 2008 to 2017. Nasopharyngeal\/throat swabs were collected from patients with influenza\u2010like illness (ILI) and severe acute respiratory illness (SARI) along with relevant epidemiological information. The samples were tested using real\u2010time reverse transcriptase\u2010polymerase chain reaction for the detection and characterization of influenza viruses. A total of 17\u2009209 samples were tested for influenza, out of which 3552 (20.6%) were positive; 2151\/11\u2009239 (19.1%) were patients with ILI, whereas 1401\/5970 (23.5%) were patients with SARI. Influenza A\/H1N1pdm09 was the predominant strain with 40.6% (n\u2009=\u20091442) followed by influenza B (936, 26.4%). Influenza A\/H1N1pdm09 was predominant among the children (5\u201014 years) and adults (15\u201064 years). Influenza B strain was predominantly found in the elderly age group (\u2265\u200965 years) accounting for 48% of cases followed by children (2\u20104 years) accounting for 37% of cases. This 10\u2010year surveillance data provides evidence of influenza activity in the country throughout the year with seasonal winter peaks. The results could be used to strengthen the epidemic preparedness and response plan.<\/jats:p>","DOI":"10.1002\/jmv.25913","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T09:20:15Z","timestamp":1587460815000},"page":"3028-3037","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Epidemiology of Influenza among patients with influenza\u2010like illness and severe acute respiratory illness in Pakistan: A 10\u2010year surveillance study 2008\u201017"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4107-6154","authenticated-orcid":false,"given":"Nadia","family":"Nisar","sequence":"first","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uzma Bashir","family":"Aamir","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazish","family":"Badar","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Rashid","family":"Mahmood","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashifa","family":"Yaqoob","sequence":"additional","affiliation":[{"name":"Research Unit Common Management Unit (HIV\/AIDS, TB &amp; Malaria)  Islamabad Pakistan"},{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2626-5977","authenticated-orcid":false,"given":"Jaya Prasad","family":"Tripathy","sequence":"additional","affiliation":[{"name":"Department of Community Medicine All India Institute of Medical Sciences  Nagpur India"},{"name":"Center of Operational Research International Union Against Tuberculosis and Lung Disease  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmay","family":"Laxmeshwar","sequence":"additional","affiliation":[{"name":"Operational Center Brussels, Sans Frontieres  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karma","family":"Tenzin","sequence":"additional","affiliation":[{"name":"Faculty of Postgraduate Medicine Khesar Gyalpo University of Medical Sciences of Bhutan  Thimphu Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Sohail Zahoor","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Salman","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aamer","family":"Ikram","sequence":"additional","affiliation":[{"name":"Department of Virology, Public Health Laboratories Division National Institute of Health  Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001977"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024579"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0079959"},{"key":"e_1_2_10_5_1","first-page":"1","article-title":"Synchrony of clinical and laboratory surveillance for influenza in Hong Kong","volume":"3","author":"Yang L","year":"2008","journal-title":"PLoS One"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)33293-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1006377"},{"key":"e_1_2_10_8_1","unstructured":"WHO | Pandemic (H1N1) 2009\u2014update 82. 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