{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:15:48Z","timestamp":1777482948021,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,6,2]],"date-time":"2020-06-02T00:00:00Z","timestamp":1591056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Rapid diagnosis and isolation are key to containing the quick spread of a pandemic agent like severe acute respiratory syndrome\u2010related coronavirus 2 (SARS\u2010CoV\u20102), which has spread globally since its initial outbreak in Wuhan province in China. SARS\u2010CoV\u20102 is novel and the effect on typically prevalent seasonal viruses is just becoming apparent. We present our initial data on the prevalence of respiratory viruses in the month of March\u00a02020.\u00a0This is a retrospective cohort study post launching of SARS\u2010CoV\u20102 testing at Baylor Scott and White Hospital (BSWH), Temple, Texas. Testing for SARS\u2010CoV\u20102 was performed by real\u2010time reverse transcription polymerase chain reaction\u00a0assay and results were shared with State public health officials for immediate interventions.\u00a0More than 3500 tests were performed during the first 2 weeks of testing for SARS\u2010CoV\u20102 and identified 168 (4.7%) positive patients. Sixty\u2010two (3.2%) of the 1912 ambulatory patients and 106 (6.3%) of the 1659 emergency department\/inpatients tested were positive. The highest rate of infection (6.9%) was seen in patients aged 25 to 34 years, while the lowest rate of infection was seen among patients aged &lt;25 years old (2%). County\u2010specific patient demographic information was shared with respective public health departments for epidemiological interventions.\u00a0Incidentally, this study showed that there was a significant decrease in the occurrence of seasonal respiratory virus infections, perhaps due to increased epidemiological awareness about SARS\u2010CoV\u20102 among the general public, as well as the social distancing measures implemented in response to SARS\u2010CoV\u20102. Data extracted for BSWH from the Centers for Disease Control and Prevention's National Respiratory and Enteric Virus Surveillance System\u00a0site revealed that Influenza incidence was 8.7% in March 2020, compared with\u00a025% in March 2019.\u00a0This study was intended to provide an initial experience of dealing with a pandemic and the role of laboratories in crisis management. This study provided SARS\u2010CoV\u20102 testing data from ambulatory and inpatient population. Epidemiological interventions depend on timely availability of accurate diagnostic tests and throughput capacity of such systems during large outbreaks like SARS\u2010CoV\u20102.<\/jats:p>","DOI":"10.1002\/jmv.26010","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T04:13:34Z","timestamp":1589516014000},"page":"2130-2138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Early trends for SARS\u2010CoV\u20102 infection in central and north Texas and impact on other circulating respiratory viruses"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0452-7382","authenticated-orcid":false,"given":"Manohar B.","family":"Mutnal","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro C.","family":"Arroliga","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Critical Care and Chief Medical Officer Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew M.","family":"Brigmon","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan M.","family":"Beaver","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Midturi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arundhati","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Baylor Scott &amp; White Medical Center  Temple Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1097"},{"key":"e_1_2_9_3_1","unstructured":"Coronavirus.https:\/\/www.who.int\/emergencies\/diseases\/novel\u2010coronavirus\u20102019. 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