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For this reason, a detailed evolutionary analysis of SARS\u2010CoV\u20102 strains currently circulating in different geographic regions of the world was performed. A compositional analysis as well as a Bayesian coalescent analysis of complete genome sequences of SARS\u2010CoV\u20102 strains recently isolated in Europe, North America, South America, and Asia was performed. The results of these studies revealed a diversification of SARS\u2010CoV\u20102 strains in three different genetic clades. Co\u2010circulation of different clades in different countries, as well as different genetic lineages within different clades were observed. The time of the most recent common ancestor\u00a0was established to be around 1st November\u00a02019. A mean rate of evolution of 6.57\u2009\u00d7\u200910<jats:sup>\u22124<\/jats:sup> substitutions per site per year was found. A significant migration rate per genetic lineage per year from Europe to South America was also observed. The results of these studies revealed an increasing diversification of SARS\u2010CoV\u20102 strains. High evolutionary rates and fast population growth characterizes the population dynamics of SARS\u2010CoV\u20102 strains.<\/jats:p>","DOI":"10.1002\/jmv.26018","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T08:14:45Z","timestamp":1589530485000},"page":"2165-2172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Evidence of increasing diversification of emerging\u00a0Severe Acute Respiratory Syndrome Coronavirus 2 strains"],"prefix":"10.1002","volume":"92","author":[{"given":"Mat\u00edas","family":"Castells","sequence":"first","affiliation":[{"name":"Laboratorio de Virolog\u00eda Molecular, Centro Universitario Regional Universidad de la Rep\u00fablica  Salto Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Lopez\u2010Tort","sequence":"additional","affiliation":[{"name":"Laboratorio de Virolog\u00eda Molecular, Centro Universitario Regional Universidad de la Rep\u00fablica  Salto Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3731-5383","authenticated-orcid":false,"given":"Rodney","family":"Colina","sequence":"additional","affiliation":[{"name":"Laboratorio de Virolog\u00eda Molecular, Centro Universitario Regional Universidad de la Rep\u00fablica  Salto Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4508-8435","authenticated-orcid":false,"given":"Juan","family":"Cristina","sequence":"additional","affiliation":[{"name":"Laboratorio de Virolog\u00eda Molecular, Centro de Investigaciones Nucleares, Facultad de Ciencias Universidad de la Rep\u00fablica  Montevideo Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25681"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2016.03.003"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1143"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211721"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30154-9"},{"key":"e_1_2_9_7_1","unstructured":"World Health Organization.2020.Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019\u2010nCoV).\u00a0https:\/\/www.who.int. 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