{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:54:33Z","timestamp":1785880473007,"version":"3.56.0"},"reference-count":12,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T00:00:00Z","timestamp":1592524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) serological assays are urgently needed for rapid diagnosis, contact tracing, and for epidemiological studies. So far, there is limited data on how commercially available tests perform with real patient samples, and if positive tested samples show neutralizing abilities. Focusing on IgG antibodies, we demonstrate the performance of two enzyme\u2010linked immunosorbent assay (ELISA) assays (Euroimmun SARS\u2010CoV\u20102 IgG and Vircell COVID\u201019 ELISA IgG) in comparison to one lateral flow assay (FaStep COVID\u201019 IgG\/IgM Rapid Test Device) and two in\u2010house developed assays (immunofluorescence assay [IFA] and plaque reduction neutralization test [PRNT]). We tested follow up serum\/plasma samples of individuals polymerase chain reaction\u2010diagnosed with COVID\u201019. Most of the SARS\u2010CoV\u20102 samples were from individuals with moderate to the severe clinical course, who required an in\u2010patient hospital stay. For all examined assays, the sensitivity ranged from 58.8 to 76.5% for the early phase of infection (days 5\u20109) and from 93.8% to 100% for the later period (days 10\u201018).<\/jats:p>","DOI":"10.1002\/jmv.26145","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T11:09:27Z","timestamp":1591614567000},"page":"2243-2247","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":108,"title":["Clinical performance of different SARS\u2010CoV\u20102 IgG antibody tests"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5458-1467","authenticated-orcid":false,"given":"Niko","family":"Kohmer","sequence":"first","affiliation":[{"name":"Institute for Medical Virology, University Hospital Goethe University Frankfurt am Main  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Westhaus","sequence":"additional","affiliation":[{"name":"Institute for Medical Virology, University Hospital Goethe University Frankfurt am Main  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"R\u00fchl","sequence":"additional","affiliation":[{"name":"Institute for Medical Virology, University Hospital Goethe University Frankfurt am Main  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Ciesek","sequence":"additional","affiliation":[{"name":"Institute for Medical Virology, University Hospital Goethe University Frankfurt am Main  Frankfurt Germany"},{"name":"German Centre for Infection Research External partner site  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger F.","family":"Rabenau","sequence":"additional","affiliation":[{"name":"Institute for Medical Virology, University Hospital Goethe University Frankfurt am Main  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9030231"},{"key":"e_1_2_5_3_1","first-page":"1","article-title":"Convalescent plasma transfusion for the treatment of COVID\u201019: systematic review","author":"Rajendran K","year":"2020","journal-title":"J Med Virol"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15562-9"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00461-20"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25800"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25919"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2196-x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.45123"},{"key":"e_1_2_5_10_1","doi-asserted-by":"crossref","unstructured":"WangB WangL KongX et al. 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