{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:11:26Z","timestamp":1789164686942,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,7,11]],"date-time":"2020-07-11T00:00:00Z","timestamp":1594425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570018"],"award-info":[{"award-number":["81570018"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this paper is to perform a meta\u2010analysis regarding the chest computed tomography (CT) manifestations of coronavirus disease\u20102019 (COVID\u201019) pneumonia patients. PubMed, Embase, and Cochrane Library databases were searched from 1 December 2019 to 1 May 2020 using the keywords of \u201cCOVID\u201019 virus,\u201d \u201cthe 2019 novel coronavirus,\u201d \u201cnovel coronavirus,\u201d and \u201cCOVID\u201019.\u201d Studies that evaluated the CT manifestations of common and severe COVID\u201019 pneumonia were included. Among the 9736 searched results, 15 articles describing 1453 common patients and 697 severe patients met the inclusion criteria. Based on the CT images, the common patients were less frequent to exhibit consolidation (odds ratio [OR]\u2009=\u20090.31), pleural effusion (OR\u2009=\u20090.19), lymphadenopathy (OR\u2009=\u20090.17), crazy\u2010paving pattern (OR\u2009=\u20090.22), interlobular septal thickening (OR\u2009=\u20090.27), reticulation (OR\u2009=\u20090.20), traction bronchiectasis (OR\u2009=\u20090.40) with over two lobes involved (OR\u2009=\u20090.07) and central distribution (OR\u2009=\u20090.18) while more frequent to bear unilateral pneumonia (OR\u2009=\u20094.65) involving one lobe (OR\u2009=\u200913.84) or two lobes (OR\u2009=\u20096.95) when compared with severe patients. Other CT features including ground\u2010glass opacities (<jats:italic>P<\/jats:italic>\u2009=\u2009.404), air bronchogram (<jats:italic>P<\/jats:italic>\u2009=\u2009.070), nodule (<jats:italic>P<\/jats:italic>\u2009=\u2009.093), bronchial wall thickening (<jats:italic>P<\/jats:italic>\u2009=\u2009.15), subpleural band (<jats:italic>P<\/jats:italic>\u2009=\u2009.983), vascular enlargement (<jats:italic>P<\/jats:italic>\u2009=\u2009.207), and peripheral distribution (<jats:italic>P<\/jats:italic>\u2009=\u2009.668) did not have a significant association with the severity of the disease. No publication bias among the selected studies was suggested (Harbord's tests,<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05 for all.) We obtained reliable estimates of the chest CT manifestations of COVID\u201019 pneumonia patients, which might provide an important clue for the diagnosis and classification of COVID\u201019 pneumonia.<\/jats:p>","DOI":"10.1002\/jmv.26218","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T16:40:09Z","timestamp":1593016809000},"page":"241-249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Meta\u2010analysis of chest CT features of patients with COVID\u201019 pneumonia"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3014-1587","authenticated-orcid":false,"given":"Ying","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suqin","family":"Ben","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.01.009"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/89.9.873"},{"key":"e_1_2_8_4_1","first-page":"805","article-title":"[Interpretation of \"Guidelines for the Diagnosis and Treatment of Novel Coronavirus (2019\u2010nCoV) Infection by the National Health Commission (Trial Version 5)\"]","volume":"100","author":"Lin L","year":"2020","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-45"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2020.108941"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.02.017"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.22976"},{"issue":"2","key":"e_1_2_8_10_1","first-page":"198","article-title":"[CT imaging features of patients with different clinical types of coronavirus disease 2019 (COVID\u201019)]","volume":"49","author":"Zhong Q","year":"2020","journal-title":"Zhejiang Da Xue Xue Bao Yi Xue Ban"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202002-0445OC"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000672"},{"key":"e_1_2_8_13_1","first-page":"1","article-title":"Clinical characteristics of 140 patients infected with SARS\u2010CoV\u20102 in Wuhan, China","author":"Zhang JJ","year":"2020","journal-title":"Allergy"},{"issue":"7","key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1097\/RLI.0000000000000689","article-title":"The performance of chest CT in evaluating the clinical severity of COVID\u201019 pneumonia: identifying critical cases based on CT characteristics","volume":"55","author":"Lyu P","year":"2020","journal-title":"Invest Radiol"},{"key":"e_1_2_8_15_1","first-page":"1","article-title":"CT features of SARS\u2010CoV\u20102 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city","volume":"11","author":"Zhang R","year":"2020","journal-title":"Eur Radiol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.45016"},{"key":"e_1_2_8_17_1","first-page":"3404","article-title":"Clinical characteristics of 161 cases of corona virus disease 2019 (COVID\u201019) in Changsha","volume":"24","author":"Zheng F","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_8_18_1","first-page":"1","article-title":"Clinical characteristics of 145 patients with corona virus disease 2019 (COVID\u201019) in Taizhou, Zhejiang, China","volume":"28","author":"Chen Q","year":"2020","journal-title":"Infection"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2020.04.001"},{"key":"e_1_2_8_20_1","first-page":"300","article-title":"A correlation study of CT and clinical features of different clinical types of COVID\u201019","volume":"54","author":"Huang L","year":"2020","journal-title":"Chin J Radiol"},{"key":"e_1_2_8_21_1","first-page":"1","article-title":"Clinical characteristics of 463 patients with common and severe type coronavirus disease","volume":"1","author":"Cheng KB","year":"2019","journal-title":"Shanghai Med J"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0118-9"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-019-1182-0"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14630-2"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211721"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30154-9"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001316"},{"key":"e_1_2_8_29_1","first-page":"1016","article-title":"Clinical and imaging features of COVID\u201019","volume":"10","author":"Chen H","year":"2020","journal-title":"Radiol Infect Dis"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/0846537120913033"},{"key":"e_1_2_8_31_1","first-page":"1","article-title":"The role of imaging in 2019 novel coronavirus pneumonia (COVID\u201019)","volume":"15","author":"Yang W","year":"2020","journal-title":"Eur Radiol"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.23034"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.5109"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13130988"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.22.suppl_1.g02oc15s137"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.3117-19"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2303030853"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2018170048"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.15.15363"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.22954"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.26218","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.26218","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.26218","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.26218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T22:05:49Z","timestamp":1696284349000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.26218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,11]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/jmv.26218"],"URL":"https:\/\/doi.org\/10.1002\/jmv.26218","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,11]]},"assertion":[{"value":"2020-03-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}