{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:47:22Z","timestamp":1791820042816,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Obesity and COVID\u201019 are both worldwide epidemics now. There may be some potential relationships between them, but little is known. This study was done to explore this relationship through literature search, systematic review, and meta\u2010analysis. Pubmed, Embase, WOS, Cochrane, CNKI, Wanfang, and Sinomed databases were searched to collect literature concerning obesity and COVID\u201019. Systematic review and meta\u2010analysis were conducted after literature screening, quality assessment, and data extraction. A total of 180 articles were initially searched after duplicate removal, and 9 were finally included in our analysis. Results show that severe COVID\u201019 patients have a higher body mass index than non\u2010severe ones (WMD\u2009=\u20092.67; 95% CI, 1.52\u20103.82); COVID\u201019 patients with obesity were more severely affected and have a worse outcome than those without (OR\u2009=\u20092.31; 95% CI, 1.3\u20104.12). Obesity may aggravate COVID\u201019.<\/jats:p>","DOI":"10.1002\/jmv.26237","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T15:09:49Z","timestamp":1593529789000},"page":"257-261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":255,"title":["Obesity aggravates COVID\u201019: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2844-8336","authenticated-orcid":false,"given":"Jun","family":"Yang","sequence":"first","affiliation":[{"name":"Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Preclinical Medicine Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Intensive Care Medicine","author":"Valle LF","year":"2020"},{"issue":"1","key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"e84","DOI":"10.1016\/j.jinf.2020.03.059","article-title":"Arterial hypertension and risk of death in patients with COVID\u201019 infection: systematic review and meta\u2010analysis","volume":"81","author":"Zuin M","year":"2020","journal-title":"J Infec"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/gnv152"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10823-013-9205-6"},{"key":"e_1_2_7_6_1","article-title":"Prevalence of obesity and severe obesity among adults: United States, 2017\u20132018","volume":"360","author":"Hales CM","year":"2020","journal-title":"NCHS Data Brief"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckx143"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.34"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.20.00097"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-020-01626-9"},{"issue":"7","key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1002\/oby.22831","article-title":"High prevalence of obesity in severe acute respiratory syndrome coronavirus\u20102 (SARS\u2010CoV\u20102) requiring invasive mechanical ventilation","volume":"28","author":"Simonnet A","year":"2020","journal-title":"Obesity"},{"key":"e_1_2_7_12_1","article-title":"Metformin and COVID\u201019: A novel deal of an old drug [published online ahead of print, 2020 Apr 29]","author":"El\u2010Arabey AA","year":"2020","journal-title":"J Med Virol"},{"issue":"2","key":"e_1_2_7_13_1","first-page":"154","article-title":"Analysis of clinical characteristics of 49 patients with coronavirus disease 2019 in Jiangxi","volume":"19","author":"Xiang TX","year":"2020","journal-title":"Chin J Respir Crit Care Med"},{"issue":"5","key":"e_1_2_7_14_1","first-page":"485","article-title":"Extrapulmonary organ damage and clinical significance in patients with coronavirus disease 2019","volume":"42","author":"Wang XF","year":"2020","journal-title":"Zhejiang Med J"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa415"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154244"},{"issue":"7","key":"e_1_2_7_17_1","first-page":"622","article-title":"Clinical characteristics and outcomes of 112 cardiovascular disease patients infected by 2019\u2010nCoV","volume":"27","author":"Peng YD","year":"2020","journal-title":"Int J Cerebrovasc Dis"},{"key":"e_1_2_7_18_1","first-page":"1","article-title":"Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID\u201019)","volume":"2","author":"Wu J","year":"2020","journal-title":"J Intern Med"},{"issue":"2","key":"e_1_2_7_19_1","first-page":"144","article-title":"Clinical characteristics of 96 hospitalized patients with coronavirus disease 2019","volume":"19","author":"Wang R","year":"2020","journal-title":"Chin J Respir Crit Care Med"},{"issue":"3","key":"e_1_2_7_20_1","first-page":"209","article-title":"Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia","volume":"43","author":"Liu M","year":"2020","journal-title":"Chin J Tuberculosis Respir Dis"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22842"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2016-0310OC"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3407306"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13034"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.120.317015"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.6775"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2020.0502"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.26237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.26237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.26237","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.26237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T05:59:50Z","timestamp":1693720790000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.26237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,5]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/jmv.26237"],"URL":"https:\/\/doi.org\/10.1002\/jmv.26237","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,5]]},"assertion":[{"value":"2020-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}