{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T03:03:18Z","timestamp":1765422198178,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Information about severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) infection in HIV\u2010infected individuals is scarce. In this prospective study, we included HIV (human immunodefeciency virus)\u2010infected individuals (people living with HIV [PLWHIV]) with confirmed SARS\u2010CoV\u20102 infection and compared them with PLWHIV negative for SARS\u2010CoV\u20102. We compared 55 cases of SARS\u2010CoV\u20102 infection with 69 asymptomatic PLWHIV negative for SARS\u2010CoV\u20102 reverse transcription\u2010polymerase chain reaction and\/or serology. There was no significant difference between SARS\u2010CoV\u20102 positive or negative patients for age distribution, gender, time with HIV infection, nadir CD4\u2010cell counts, type and number of co\u2010morbidities, current CD4 and CD8 counts and type of anti\u2010HIV therapy. Positive patients presented with a median of three symptoms (interquartile range, 1\u20103). Most common symptoms were fever (76%), dyspnea (35%), anosmia (29%) non\u2010productive cough (27%), fatigue 22%), and ageusia (20%). Ten patients (18%) were completely asymptomatic. Four (7.2%) subjects died of coronavirus disease 2019. Factors significantly (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) associated with death included age and number of co\u2010morbidities, while time from HIV infection and lower current CD4 counts were significant only in univariate analysis. HIV\u2010infected individuals are not protected from SARS\u2010CoV\u20102 infection or have a lower risk of severe disease. Indeed, those with low CD4 cell counts might have worse outcomes. Infection is asymptomatic in a large proportion of subjects and this is relevant for epidemiological studies.<\/jats:p>","DOI":"10.1002\/jmv.26352","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T14:21:35Z","timestamp":1595600495000},"page":"1145-1149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["SARS\u2010CoV\u20102 infection in persons living with HIV: A single center prospective cohort"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9791-0072","authenticated-orcid":false,"given":"Franco","family":"Maggiolo","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases ASST Papa Giovanni XXIII  Bergamo Italy"},{"name":"Department of Medicine, Unit of HIV related diseases and experimental therapies ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Zoboli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Arosio","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Biobanking Unit ASST Papa Giovanni XXIII  Bergamo Italy"},{"name":"Department of Laboratory, Microbiology and Virology Laboratory ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Valenti","sequence":"additional","affiliation":[{"name":"Department of Medicine, Unit of HIV related diseases and experimental therapies ASST Papa Giovanni XXIII  Bergamo Italy"},{"name":"FROM Foundation ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Guarneri","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Biobanking Unit ASST Papa Giovanni XXIII  Bergamo Italy"},{"name":"Department of Laboratory, Microbiology and Virology Laboratory ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Sangiorgio","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Biobanking Unit ASST Papa Giovanni XXIII  Bergamo Italy"},{"name":"Department of Laboratory, Microbiology and Virology Laboratory ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Ripamonti","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annapaola","family":"Callegaro","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Biobanking Unit ASST Papa Giovanni XXIII  Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1097"},{"volume-title":"WHO Director\u2010General's opening remarks at the media briefing on COVID\u201019\u201411 March 2020","author":"WHO","key":"e_1_2_8_3_1"},{"key":"e_1_2_8_4_1","unstructured":"Italian Ministry of Health (Ministero della Salute).Novel coronavirus.http:\/\/www.salute.gov.it\/portale\/nuovocoronavirus\/homeNuovoCoronavirus.jsp?lingua=english. 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