{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:11:13Z","timestamp":1791313873133,"version":"4.3.1"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The novel coronavirus severe acute respiratory syndrome coronavirus 2 (<jats:bold>SARS\u2010CoV\u20102<\/jats:bold>) has kept the whole world in tenterhooks due to its severe life\u2010threatening infectious disease, COVID\u201019. The virus is distinct from its cousins, SARS\u2010CoV\u00a0and MERS\u2010CoV in terms of severity of the infection. The obligated killing properties of the SARS\u2010CoV\u20102 virus is mediated by its unique structure. Efforts for developing vaccines for COVID\u201019 are ongoing, but it is unlikely to be available in the immediate future. Due to the absence of precise treatment, the investigators are discovering other effective, protective, and healing choices. However, the lower than a predictable number of SARS\u2010CoV\u20102 cases in countries with fragile health systems is mystifying. Recently, there has been a buzz about the protective effect of Bacille Calmette\u2010Gu\u00e9rin (<jats:bold>BCG<\/jats:bold>) vaccine in COVID\u201019 through long\u2010term boosting of trained immunity. Based on <jats:bold>epidemiological correlations<\/jats:bold>, we link up that BCG vaccination adopted by different countries might influence the SARS\u2010CoV\u20102 transmission patterns and\/or COVID\u201019 associated mortality through the vaccine's capacity to confer heterologous protection. A number of clinical studies are underway to investigate this possibility but even if they prove effective\u2010many questions will remain. Moreover, responsible <jats:bold>stewardship of the BCG<\/jats:bold> vaccine in the context of the COVID\u201019 epidemic is directly needed.<\/jats:p>","DOI":"10.1002\/jmv.26450","type":"journal-article","created":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T14:12:26Z","timestamp":1598105546000},"page":"1496-1505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Convergence between global BCG vaccination and COVID\u201019 pandemic"],"prefix":"10.1002","volume":"93","author":[{"given":"Md. Zahurul","family":"Islam","sequence":"first","affiliation":[{"name":"Department of Applied Mathematics University of Rajshahi  Rajshahi Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. 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