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For the prophylactics, the medical staff was prevented from pre\u2010exposure prophylaxis (risk prevention of exposure to COVID\u201019 patients before using thymosin drugs) and postexposure prophylaxis (risk prevention of exposure to COVID\u201019 patients after using thymosin drugs). The effectiveness and safety of thymosin drugs were studied in the prevention and control of COVID\u201019 application, in real\u2010world data research for the application of the drug for\u00a0COVID\u2010 19.\u00a0In a similar exposure environment, compared to medical staffers who did not take preventive medicine, the use of thymosin drugs, before exposure and after exposure had an insignificant effect, and the adverse drug reaction (ADR) was increased, especially when thymosin drugs were used together with \u03b1\u2010interferon.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.26492","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T07:40:04Z","timestamp":1599723604000},"page":"1573-1580","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Analysis of the\u00a0prophylactic effect of thymosin drugs on COVID\u201019 for 435 medical staff: A hospital\u2010based retrospective study"],"prefix":"10.1002","volume":"93","author":[{"given":"Xiulan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Pharmacy,\u00a0Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology  Wuhan Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy,\u00a0Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology  Wuhan Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liuming","family":"Wang","sequence":"additional","affiliation":[{"name":"Nursing Department,\u00a0Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology  Wuhan Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luhong","family":"Hu","sequence":"additional","affiliation":[{"name":"Medical Office, Tongji Hospital 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