{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T14:37:23Z","timestamp":1775918243399,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human herpesvirus 8 (HHV\u20108) seroprevalence varies geographically and between subpopulations. High seroprevalence rates have been ascribed to men who have sex with men (MSM), African migrants, and HIV\u2010infected individuals. The objective of this study was to determine the seroprevalence of HHV\u20108 in an Irish population, including specific risk groups. A cross\u2010sectional study of 200 blood donors and 200 genitourinary medicine (GUM) and infectious diseases (ID) clinic patients was performed, with testing for Immunoglobulin G\u00a0(IgG) antibodies to HHV\u20108 lytic antigens using a commercial indirect fluorescence assay (Scimedx Corp.). Verification was performed at the Centers for Disease Control and Prevention (CDC). All 200 blood donor samples were negative for HHV\u20108 IgG antibodies. 21% of GUM and ID patients were positive for HHV\u20108 IgG antibodies. One hundred\u00a0of these patients were MSM, 35% of whom were HHV\u20108 seropositive (46% of HIV\u2010positive MSM and 24% of HIV\u2010negative MSM). Of 100 heterosexual patients, only 7% were HHV\u20108 seropositive. The absence of seropositivity in 200 Irish blood donors may suggest that Ireland has a low overall population HHV\u20108 seroprevalence. The proportion of HHV\u20108 seropositivity in the MSM population was significantly higher than in the heterosexual population and most marked in HIV\u2010positive MSM.<\/jats:p>","DOI":"10.1002\/jmv.26813","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T18:45:23Z","timestamp":1611254723000},"page":"5058-5064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Seroprevalence of human herpesvirus 8 in Ireland among blood donors, men who have sex with men, and heterosexual genitourinary medicine and infectious diseases clinic attendees"],"prefix":"10.1002","volume":"93","author":[{"given":"Sadhbh","family":"O'Rourke","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology St. James's Hospital  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niamh","family":"O'Flaherty","sequence":"additional","affiliation":[{"name":"Irish Blood 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