{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T09:35:49Z","timestamp":1775036149921,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T00:00:00Z","timestamp":1620172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>There are concerns regarding the side effects of the new coronavirus disease 2019 (COVID\u201019) mRNA\u20101273 vaccine among healthcare workers (HCWs) in the United States. The objective of the study was to investigate the side effects of the mRNA\u20101273 vaccine with detailed review of organ systems. A randomized, cross\u2010sectional study using an independent online survey questionnaire was conducted to collect responses from HCWs. Of all participants, 87.8% (1116\/1271) provided complete responses. Of them, 38.7% (432\/1116) received the mRNA\u20101273 vaccine, among which, 89.35% were females; 425 of these 432 mRNA\u20101273 vaccine recipients (98.34%) reported at least one or more symptoms. The results were classified based on the frequency of symptoms reported postvaccination. Of these, 254\/432 (58.8%) were able to continue their daily routine activities. 108\/432 (25%) temporarily had trouble to perform daily activities, 120\/432 (27.78%) required transient time off from work, 17\/432 (3.94%) required help from an outpatient provider, 1\/432 (0.23%) required help from emergency department, and none of them were hospitalized. Despite the wide array of self\u2010reported symptoms, 97.02% of the HCWs did not intend to skip the second dose of vaccine. Among all the symptoms reported, localized pain, generalized weakness, headache, myalgia, chills, fever, nausea, joint pains, sweating, localized swelling at the injection site, dizziness, itching, rash, decreased appetite, muscle spasm, decreased sleep quality, and brain fogging were the most commonly reported symptoms (in descending order of occurrence). Most of the symptoms reported were nonlife threatening. Despite the wide array of self\u2010reported symptoms, there appears to be a higher acceptance for this vaccine.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.26996","type":"journal-article","created":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T10:24:01Z","timestamp":1617704641000},"page":"4420-4429","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["Non\u2010life\u2010threatening adverse effects with COVID\u201019 mRNA\u20101273 vaccine: A randomized, cross\u2010sectional study on healthcare workers with detailed self\u2010reported symptoms"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4105-7743","authenticated-orcid":false,"given":"Renuka Ananth Kalyan","family":"Kadali","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Harnett Health System Affiliated with Cape Fear Valley Health System Lillington North Carolina USA"},{"name":"Department of Internal Medicine Campbell University Jerry M. Wallace School of Osteopathic Medicine Lillington North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7601-7648","authenticated-orcid":false,"given":"Ravali","family":"Janagama","sequence":"additional","affiliation":[{"name":"Kidzcare Pediatrics Sanford North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharanya","family":"Peruru","sequence":"additional","affiliation":[{"name":"Department of Statistics North Carolina State University Raleigh North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viswanath","family":"Gajula","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Critical Care Medicine University of Mississippi Medical Center Jackson Mississippi USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajasekhar R.","family":"Madathala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhita","family":"Chennaiahgari","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srikrishna V.","family":"Malayala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Temple University Hospital Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17687-3"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.17.2000257"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(20)30126-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(20)30145-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2020.04.048"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1127"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14888"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03009-y"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2020.101623"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1515\/revneuro-2020-0066"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03006-2020"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.5863\/1551-6776-25.7.574"},{"key":"e_1_2_11_14_1","unstructured":"COVID Data Tracker. 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