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Clinical specimens were collected from 46\u2009365 patients at Beijing Friendship Hospital, Capital Medical University from January 2017 to December 2020. HPV DNA genotype testing was performed using real\u2010time PCR. The infection rates based on disease group were compared using the <jats:italic>\u03c7<\/jats:italic>\n<jats:sup>2<\/jats:sup> test. The linear\u2010by\u2010linear association test and gamma value were used to assess the changes in HPV prevalence over calendar year and age group. A total of 10\u2009514 women were infected with HR\u2010HPV, with an overall positive rate of 22.7%. The most prevalent HR\u2010HPV types were HPV52, 58, 16, 51, and 66, and HPV59 had a higher prevalence except for HPV16, 58, and 52 in the CC group. Single infection of HR\u2010HPV was dominant among different disease groups. The infection rate of HR\u2010HPV decreased first and then increased from below 20 years old to over 60 years old. There were significant differences in the HR\u2010HPV infection rates among the age and disease groups. Our findings demonstrate that the genotype distribution of HR\u2010HPV varied with age and diseases. The HR\u2010HPV genotypes prevalence was found to be directly useful for local governments to promote HPV targeted vaccination in the study region.<\/jats:p>","DOI":"10.1002\/jmv.27013","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T21:14:11Z","timestamp":1618348451000},"page":"5103-5109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Prevalence and genotype distribution of high\u2010risk HPV infection among women in Beijing, China"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6510-3412","authenticated-orcid":false,"given":"Xiaoyan","family":"Zhu","sequence":"first","affiliation":[{"name":"Clinical Laboratory Center, Beijing Friendship Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Center, Beijing Friendship Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Lv","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Center, Beijing Friendship Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianrong","family":"Su","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Center, Beijing Friendship Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31937"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4424"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25396"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70158-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67069-9"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24248"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph120910794"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.04.023"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2019.1661757"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/657321"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-014-0708-8"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3105-x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4038-8"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-019-0785-3"},{"issue":"9","key":"e_1_2_9_16_1","first-page":"11901","article-title":"Distribution of HPV genotypes in Shanghai women","volume":"8","author":"Singh S","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24281"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.14971"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2498-2"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-017-0751-3"},{"key":"e_1_2_9_21_1","unstructured":"HPV WIICo Cervical C.HPV and cervical cancer in the 2007 report. 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