{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:41:41Z","timestamp":1762508501234,"version":"3.37.3"},"reference-count":14,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>The new type of coronavirus could cause severe acute respiratory syndrome and injuries in other systems as well. Multiple organ damage can occur rapidly in patients infected with coronavirus disease 2019 (COVID\u201019). Previous studies have shown that many laboratory biomarkers were not within the normal ranges in COVID\u201019 patients. We aimed to summarize laboratory parameters and the tumor markers in COVID\u201019 patients. This is a retrospective cohort study conducted on 53 women between the ages of 19\u201385 years infected with COVID\u201019 at a training and research hospital between May 2020 and August 2020.\u00a0Of the 53 women, 16 (30.2%) had leukopenia. The mean C\u2010reactive protein level was 18.42\u2009\u00b1\u200959.33\u2009mg\/L. The mean procalcitonin level was 0.1\u2009\u00b1\u20090.21\u2009\u00b5g\/L. The liver function tests were within normal limits. The mean creatinine level was 0.58\u2009\u00b1\u20090.37 mg\/dl. Elevated levels of \u03b1\u2010fetoprotein (AFP)\u00a0in 1 patient, elevated levels of carcinoembryonic antigen (CEA) in 2 patients, elevated levels of cancer antigen 125 (CA125)\u00a0in 4 patients, elevated levels of CA19\u20109 in 2 patients, and elevated levels of CA15\u20103 in 2 patients were detected. One of 4 patients who were taken to the intensive care unit had elevated levels of AFP. In addition, 2 of 4 patients who were taken to the intensive care unit had elevated levels of CA125 and CA15\u20103. Except for AFP, levels of all tumor markers of the patient who died were high. We found that COVID\u201019 had no effect on tumor markers (CA125, CA19\u20109, CA15\u20103, AFP, and CEA).<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.27057","type":"journal-article","created":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T17:06:06Z","timestamp":1619888766000},"page":"5405-5408","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of the coronavirus pandemic on tumor markers"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5779-3847","authenticated-orcid":false,"given":"Yunus Emre","family":"Purut","sequence":"first","affiliation":[{"name":"Clinic of Obstetrics and Gynecology, Van Training and Research Hospital University of Health Sciences  Kilometre Edremit Van Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3832-6634","authenticated-orcid":false,"given":"Burak","family":"Giray","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology,\u00a0\u015eehit Prof. Dr. \u0130lhan Varank Sancaktepe Training and Research Hospital University of Health Sciences  Sancaktepe \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3123-0963","authenticated-orcid":false,"given":"Esra","family":"Gurbuz","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Van Training and Research Hospital University of Health Sciences  Kilometre Edremit Van Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1770129"},{"key":"e_1_2_8_4_1","first-page":"1","article-title":"Usefulness of biological markers in the early prediction of corona virus disease\u20102019 severity","volume":"18","author":"Bennouar S","year":"2015","journal-title":"Scand J Clin Lab Invest"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2014.992944"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.06.018"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25957"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.41.1.17"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-014-1976-1"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/2278-0513.134477"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.03.035"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gore.2020.100644"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.13450"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2020.05.069"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.27057","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T15:58:08Z","timestamp":1692979088000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.27057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,12]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1002\/jmv.27057"],"URL":"https:\/\/doi.org\/10.1002\/jmv.27057","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"type":"print","value":"0146-6615"},{"type":"electronic","value":"1096-9071"}],"subject":[],"published":{"date-parts":[[2021,6,12]]},"assertion":[{"value":"2021-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}