{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T04:55:45Z","timestamp":1768193745018,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>It was aimed to evaluate long\u2010term radiological changes in\u00a0severe coronavirus disease 2019 (COVID\u201019) patients, to investigate pulmonary function, exercise capacities, and health\u2010related quality of life results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010five patients with severe COVID\u201019 pneumonia were evaluated in the sixth month after discharge from the hospital. Spirometry, 6\u2009min walking test (6MWT), and short form of health\u2010related quality of life scale (SF\u201036) were applied in the sixth month. Chest computed tomography (CT) was performed and the findings were grouped according to lung involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010nine\u00a0male and 16 female patients were included in the study. Forced expiratory volume in 1\u2009s (FEV1)% values of 18 patients (30.5%), forced vital capacity (FVC)% values of 27 patients (45.8%), and 6MWT of 13 patients (23.2%) were found lower than expected in the sixth month. On the SF\u201036 scale, physical function, energy\u2010vitality, social functionality, pain, and general health parameters were found lower than normal. Minimal interstitial changes in chest CT were seen in 26 patients. Nine patients had lung area involvement between 10% and 50% of the surface, there was a correlation between FEV1% and FVC% values in this group. There was severe pulmonary fibrosis in four patients. There was a correlation between pulmonary function and physical function and general perception of health from SF\u201036 scale subparameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Functional and radiological abnormalities were detected in a significant number of patients in the sixth month\u00a0after severe COVID\u201019 pneumonia. A systematic monitoring plan must be established to assess and properly manage the long\u2010term problems that may arise.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.27101","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:53:19Z","timestamp":1621936399000},"page":"5574-5581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Evaluation of long\u2010term radiological findings, pulmonary functions, and health\u2010related quality of life in survivors of severe COVID\u201019"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9038-4049","authenticated-orcid":false,"given":"Mustafa Ilteris","family":"Bardakci","sequence":"first","affiliation":[{"name":"Department of Chest Diseases, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6652-3582","authenticated-orcid":false,"given":"Esin Nagihan","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8345-4539","authenticated-orcid":false,"given":"Mufide Arzu","family":"Ozkarafakili","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huseyin","family":"Ozkurt","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugur","family":"Yanc","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6047-4879","authenticated-orcid":false,"given":"Dilek","family":"Yildiz Sevgi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Sisli Hamidiye Training and Research Hospital University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Republic of Turkey Ministry of Health General Directorate of Public Health. Covid\u201019 (SARS\u2010CoV\u20102 infection) Guideline. 2020."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.12839"},{"key":"e_1_2_10_4_1","unstructured":"World Health Organization. Coronavirus disease 2019 (COVID\u201019) situation report. 2021.https:\/\/covid19.who.int\/. Accessed February 18 2021."},{"key":"e_1_2_10_5_1","article-title":"COVID\u201019 Pn\u00f6monisinin Radyolojik Bulgular\u0131","author":"C\u00f6mert S\u015e","year":"2020","journal-title":"Southern Clinics of Istanbul Eurasia"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2004.030205"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00007104"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.09.025"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-5231(05)70060-5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.166.1.at1102"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.3.7663792"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00035005"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2017.04.005"},{"key":"e_1_2_10_14_1","first-page":"102","article-title":"Validity and reliability of Turkish version of Short form 36: a study of a patients with romatoid disorder","volume":"12","author":"Kocyigit H","year":"1999","journal-title":"\u0130la\u00e7 ve Tedavi Dergisi"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.22969"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30566-3"},{"key":"e_1_2_10_17_1","article-title":"Long term clinical outcames in survivors of severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus outbreaks after hospitalisation or ICU admission: a systematic rewiew and meta\u2010analysis","volume":"52","author":"Ahmed H","year":"2020","journal-title":"J Rehebil Med"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011802"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03690-2020"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.04015-2020"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32656-8"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2020.106272"},{"key":"e_1_2_10_23_1","first-page":"81","article-title":"Anormal pulmonary function and residual CT abnormalities in rehabilitating COVID\u201019 patients after discharge","volume":"81","author":"You J","year":"2020","journal-title":"Infection"},{"key":"e_1_2_10_24_1","first-page":"1","article-title":"Pulmonary function in patients surviving to COVID\u201019 pneumonia","author":"Fumagalli A","year":"2020","journal-title":"Infection"},{"key":"e_1_2_10_25_1","article-title":"Follow\u2010up study of the pulmonary function and related physiological characteristics of COVID\u201019 survivor three months after recovery","volume":"25","author":"Zhao YM","year":"2020","journal-title":"Eclin Med"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.00668"},{"key":"e_1_2_10_27_1","article-title":"Post\u2010discharge critical COVID\u201019 lung function related to severity of radiologic lung involvement at admission","volume":"29","author":"Truffaut L","year":"2021","journal-title":"Respiratory Res"},{"key":"e_1_2_10_28_1","article-title":"Six\u2010month follow\u2010up chest CT findings after sever COVID\u201019 pneumonia","author":"Han X","year":"2021","journal-title":"Radiology"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.27101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T15:58:17Z","timestamp":1692979097000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.27101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,31]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1002\/jmv.27101"],"URL":"https:\/\/doi.org\/10.1002\/jmv.27101","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,31]]},"assertion":[{"value":"2021-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}