{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:01:51Z","timestamp":1792184511902,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study is aimed to identify the adverse effects associated with three types of coronavirus disease 2019 vaccines. Approximately 1736 individuals agreed to participate in this study. The participants involved in the study were individuals who had received the first dose or full course (two doses) of the vaccine at least 30 days before the survey. A direct and interactive web\u2010based system interview with a paper and electronic version of the questionnaire was used for all participants. A total of 1736 randomized individuals were identified. The reactogenicity of the vaccines including pain, redness, urticaria, and swelling at the site of the injection was reported in 34.56% of the participants. Local site reaction was reported in more individuals who had Pfizer and AstraZeneca vaccines than those who received the Sinopharm vaccine. The systemic events were more common with AstraZeneca and Pfizer vaccines, symptoms reported were fatigue, body pain, headache, muscle pain, fever, and gastrointestinal side effects. There were no correlations between age or gender, and the duration of the adverse effects for the three vaccines. Swelling and severe allergic reaction of the eyelids, severe hypotension, generalized body aches, shortness of breath, weakness and numbness on the injected arm, acute hyperglycemia, severe chest pain, and fever more than 39\u00b0C were among the unusual signs and symptoms reported by the participants. Pfizer, AstraZeneca, and Sinopharm vaccines were found to be safe and Sinopharm vaccine showed a lower prevalence of adverse effects compared with the other vaccines. The duration and severity of adverse effects were not affected by age or gender. Unusual side effects should be closely monitored to establish determine they are linked to the immunization.<\/jats:p>","DOI":"10.1002\/jmv.27214","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T13:26:39Z","timestamp":1626441999000},"page":"6588-6594","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":138,"title":["Safety of COVID\u201019 vaccines"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1165-008X","authenticated-orcid":false,"given":"Qutaiba A.","family":"Al Khames Aga","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Pharmacy Philadelphia University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waseem H.","family":"Alkhaffaf","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine Ninevah University  Mosul Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tagreed H.","family":"Hatem","sequence":"additional","affiliation":[{"name":"Department of Gynecology Bagdad Teaching Hospital, Medical City  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kawthar F.","family":"Nassir","sequence":"additional","affiliation":[{"name":"Department of Gynecology Bagdad Teaching Hospital, Medical City  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazan","family":"Batineh","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Pharmacy Philadelphia University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah T.","family":"Dahham","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Pharmacy Philadelphia University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimah","family":"Shaban","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Pharmacy Philadelphia University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luma A.","family":"Al Khames Aga","sequence":"additional","affiliation":[{"name":"COVID\u201019 Testing Specialist Atechy Group Cardiff  Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manhal Y. R.","family":"Agha","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Cardiff University Hospital of Wales  Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muaamar","family":"Traqchi","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Pharmacy Philadelphia University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1124-9"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9030605"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-016-0285-9"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202000172"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.583252"},{"key":"e_1_2_10_8_1","first-page":"8","article-title":"Vaccine safety, efficacy, and trust take time","author":"Dermody TS","year":"2020","journal-title":"Ann Rev Virol"},{"key":"e_1_2_10_9_1","volume-title":"Vaccines: The Biggest Medical Fraud in History","author":"Nguyen T","year":"2018"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7008e3"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2020-0716-SA"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fmre.2021.01.011"},{"key":"e_1_2_10_13_1","unstructured":"PlumlyKM.Pharmacists as Immunizes: Increasing Non\u2010influenza Adult Immunization Rates. Drew University;2020."},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2021189117"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.10.039"},{"key":"e_1_2_10_16_1","first-page":"15","article-title":"Structure and function of COVID\u201019 Encode Proteins In The Transcription And Replication Mechanism With Its Preventive Measures And Propose Efficacy Treatments: A Critical Systematic Review","author":"Oguh C","year":"2020","journal-title":"Asian J Immunol"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1188\/10.CJON.E10-E21"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31605-6"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n699"},{"key":"e_1_2_10_20_1","unstructured":"FinbergRW.No vaccine side effects don't tell you how well your immune system will protect you from COVID\u201019.2021."},{"key":"e_1_2_10_21_1","first-page":"1","article-title":"Adverse events reported from COVID\u201019 vaccine trials: a systematic review","author":"Kaur RJ","year":"2021","journal-title":"Indian J Clin Biochem"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.27214","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T23:23:49Z","timestamp":1693005829000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.27214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,28]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1002\/jmv.27214"],"URL":"https:\/\/doi.org\/10.1002\/jmv.27214","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,28]]},"assertion":[{"value":"2021-06-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}