{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:36:37Z","timestamp":1760189797900},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T00:00:00Z","timestamp":1631232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recently, the coronavirus disease 2019 (COVID\u201019) has caused a global pandemic. Several studies indicate that the digestive system can also be affected by the severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102). Therefore, patients with digestive symptoms should have a capsule endoscopy (CE). COVID\u201019 patients with gastrointestinal (GI) symptoms who underwent CE were recruited from March 2020 to April 2020. We collected patients\u2019 data and performed a prospective follow\u2010up study for 6 months. All 11 COVID\u201019 cases with GI symptoms who underwent CE presented gastritis. Eight cases (72.7%) had intestinal mucosa inflammation. Among them, two cases showed intestinal ulcers or erosions. Moreover, two cases displayed colonic mucositis. One case was lost during follow\u2010up. At 3\u20136 months after hospital\u00a0discharge, five patients underwent CE again, presenting gastrointestinal lesions. Five of the 10 cases had GI symptoms, such as abdominal pain, diarrhea, constipation, and others. Among these five cases, the GI symptoms of three patients disappeared at the last follow\u2010up and two patients still presented diarrhea symptoms. Overall, we observed damaged digestive tract mucosa that could be caused by SARS\u2010CoV\u20102. Moreover, after discharge, some patients still presented intestinal lesions and GI symptoms.<\/jats:p>","DOI":"10.1002\/jmv.27308","type":"journal-article","created":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T14:41:59Z","timestamp":1630334519000},"page":"246-252","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Features of capsule endoscopy in COVID\u201019 patients with a six\u2010month follow\u2010up: A prospective observational study"],"prefix":"10.1002","volume":"94","author":[{"given":"Xiao\u2010Ping","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Ping","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao\u2010Qun","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Hua","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province 430022 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001316"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1585"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-320926"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20-0991"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25795"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0912-6"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2005.05.009"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1570"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030747"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211721"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15048"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastro.2003.08.001"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.052"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30251-8"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.02.055"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11228"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.27308","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T17:40:14Z","timestamp":1692985214000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.27308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,10]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1002\/jmv.27308"],"URL":"https:\/\/doi.org\/10.1002\/jmv.27308","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,10]]},"assertion":[{"value":"2021-07-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}