{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:56:41Z","timestamp":1771912601542,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Varicella is a highly contagious disease caused by the varicella\u2010zoster virus (VZV). Given its tendency to cluster geographically, spatial analyses may provide a better understanding of the pattern of varicella transmission. We investigated the spatial characteristics of varicella in Korea and the risk factors for varicella at a national level. Using national surveillance and demographic data, we examined the spatial distribution of incidence rates and their spatial autocorrelation and calculated Moran's index. Spatial regression analysis was used to identify sociodemographic predictors of varicella incidence at the district level. An increasing tendency in the annual incidence of varicella was observed over a 12\u2010year period (2006\u20132018), with a surge in 2017. There was a clear positive spatial autocorrelation of the varicella incidence rate during the surveillance period. During 2006\u20132014, High\u2010High (HH) clusters were mostly confined to the northeast region and neighboring districts. The spatial error model showed that population density had a negative coefficient and childhood percentage, percentage of children under 12 years of age among the total population, had positive coefficient, whereas vaccine coverage was insignificant. The varicella incidence according to geographic region varied with population density, childhood percentage, suggesting the importance of community\u2010level surveillance and monitoring strategies.<\/jats:p>","DOI":"10.1002\/jmv.27434","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T07:27:05Z","timestamp":1636097225000},"page":"703-712","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Spatiotemporal distribution of varicella in the Republic of Korea"],"prefix":"10.1002","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-993X","authenticated-orcid":false,"given":"Young Hwa","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Epidemiology, School of Public Health Seoul National University  Seoul Republic of Korea"},{"name":"Department of Pediatrics Korea University Anam Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-0715","authenticated-orcid":false,"given":"Young June","family":"Choe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Korea University Anam Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1558-7831","authenticated-orcid":false,"given":"Seung\u2010sik","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4085-1494","authenticated-orcid":false,"given":"Sung\u2010il","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"25","article-title":"Varicella zoster virus: natural history and current therapies of varicella and herpes zoster","volume":"14","author":"Breuer J","year":"2007","journal-title":"Herpes J\u00a0IHMF"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/pch\/21.2.91"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.9.3.361"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002233"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.1.70-80.2005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2018.1546525"},{"issue":"25","key":"e_1_2_9_8_1","first-page":"265","article-title":"Varicella and herpes zoster vaccines: WHO position paper, June 2014","volume":"89","author":"Organization WH","year":"2014","journal-title":"Wkly Epidemiol\u00a0Rec\u00a0= Relev\u00e9 \u00e9pid\u00e9miologique hebdomadaire"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)90144-5"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2165\/0063030-200822060-00005"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.17.2250-b"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.12.032"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268811001786"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.4161\/hv.36157"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2017.1247700"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-303"},{"key":"e_1_2_9_17_1","unstructured":"National Childhood Vaccination Coverage. 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