{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T13:56:39Z","timestamp":1724421399818},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>COVID\u201019 vaccines provide high levels of protection against severe disease and hospitalization due to severe acute respiratory syndrome\u2010related coronavirus 2 (SARS\u2010CoV\u20102) infection. Vaccination may be less effective in preventing shedding of infectious viruses from otherwise immune patients. In this study, we describe breakthrough infections and shedding of infectious viruses in convalescent hamsters without significant replication in the lower respiratory tract following reinfection by Alpha and Delta variants despite high levels of circulating antibodies in sera. Using convalescent hamsters with long\u2010term immunity (up to 1 year) following infection by ancestral SARS\u2010CoV\u20102, we can model aspects of recurring COVID\u201019 in the context of preexisting immunity.<\/jats:p>","DOI":"10.1002\/jmv.27641","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T02:13:45Z","timestamp":1644200025000},"page":"2833-2836","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term immunity in convalescent Syrian hamsters provides protection against new\u2010variant SARS\u2010CoV\u20102 infection of the lower but not upper respiratory tract"],"prefix":"10.1002","volume":"94","author":[{"given":"Charles B.","family":"Stauft","sequence":"first","affiliation":[{"name":"Division of Viral Products Center for Biologics Evaluations and Research, Food and Drug Administration Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhuanand","family":"Selvaraj","sequence":"additional","affiliation":[{"name":"Division of Viral Products Center for Biologics Evaluations and Research, Food and Drug Administration Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher Z.","family":"Lien","sequence":"additional","affiliation":[{"name":"Division of Viral Products Center for Biologics Evaluations and Research, Food and Drug Administration Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew F.","family":"Starost","sequence":"additional","affiliation":[{"name":"Division of Veterinary Resources Diagnostic and Research Services Branch, National Institutes of Health Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony T.","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Viral Products Center for Biologics Evaluations and Research, Food and Drug Administration Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa644"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00507-21"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.202000886"},{"key":"e_1_2_8_5_1","article-title":"Increased close proximity airborne transmission of the SARS\u2010CoV\u20102 Delta variant","volume":"176","author":"Mikszewski A","year":"2021","journal-title":"Sci Total Environ"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2021.100252"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taab124"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26672-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(21)00648-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2021.01.005"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2019.09.003"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27641","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.27641","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.27641","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T14:49:03Z","timestamp":1692974943000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.27641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/jmv.27641"],"URL":"https:\/\/doi.org\/10.1002\/jmv.27641","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]},"assertion":[{"value":"2021-12-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}