{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:46:32Z","timestamp":1790624792043,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Low temperature and certain humidity are conducive to severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) for long\u2010time survival and long\u2010distance spread during logistics and trades. Contaminated cold\u2010chain or frozen products and outer packaging act as the carrier of SARS\u2010CoV\u20102, that infects the high\u2010risk population who works in the ports, cold storage or seafood market. Since the coronavirus disease 2019 (COVID\u201019) pandemic worldwide, multiple localized outbreaks caused by SARS\u2010CoV\u20102 contaminated imported cold\u2010chain products have been reported in China, which brought challenges to COVID\u201019 prevention and control. Here, we review the evidences of SARS\u2010CoV\u20102 cold\u2010chain transmission from six confirmed cold\u2010chain related COVID\u201019 outbreaks in China, especially in terms of SARS\u2010CoV\u20102 whole\u2010genome sequencing and virus isolation. In addition, we summarize the characteristics and mode of SARS\u2010CoV\u20102 cold\u2010chain transmission from both six COVID\u201019 outbreaks in China and the outbreaks suspected cold\u2010chain transmission in other countries. Finally, we analyze the underlying risks of SARS\u2010CoV\u20102 cold\u2010chain transmission and propose the preventive countermeasures.<\/jats:p>","DOI":"10.1002\/jmv.27750","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T04:40:51Z","timestamp":1648701651000},"page":"3540-3547","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["SARS\u2010CoV\u20102 cold\u2010chain transmission: Characteristics, risks, and strategies"],"prefix":"10.1002","volume":"94","author":[{"given":"Cao","family":"Chen","sequence":"first","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention  102206 Beijing China"},{"name":"Key Laboratory of Medical Virology and Viral Diseases Ministry of Health of the People's Republic of China  Beijing China"},{"name":"Center for Biosafety Mega\u2010Science Chinese Academy of Sciences  Wuhan 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xia","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention  102206 Beijing China"},{"name":"Key Laboratory of Medical Virology and Viral Diseases Ministry of Health of the People's Republic of China  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention  102206 Beijing China"},{"name":"Key Laboratory of Medical Virology and Viral Diseases Ministry of Health of the People's Republic of China  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Wang","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Han","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention  102206 Beijing China"},{"name":"Center for Biosafety Mega\u2010Science Chinese Academy of Sciences  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Xu","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention  102206 Beijing China"},{"name":"Key Laboratory of Medical Virology and Viral Diseases Ministry of Health of the People's Republic of China  Beijing 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Report 2020."},{"key":"e_1_2_11_19_1","unstructured":"Almost 100 staff at food factories test positive for Coronavirus. Farming Online 2020. Available fromhttps:\/\/farming.co.uk\/news\/almost-100-staff-at-food-factories-test-positive-for-coronavirus"},{"key":"e_1_2_11_20_1","unstructured":"Covid\u201019 spike forces Singapore to close major seafood import port. Seafood Source 2021. Available fromhttps:\/\/www.seafoodsource.com\/news\/supply-trade\/covid-19-spike-forces-singapore-to-close-major-seafood-import-port"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18052633"},{"key":"e_1_2_11_22_1","unstructured":"World Health Organization. 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