{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:37:08Z","timestamp":1774525028592,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The control of the COVID\u201019 epidemics has been one global health priorities for the last 2 years. To that end, more reliable and easy\u2010to\u2010use, regardless of age, diagnostic tests are necessary. Considering that, we evaluated an innovative two\u2010step self\u2010test, the AAZ COVID\u2010VIRO ALL IN\u00ae, switching from the classic nasal swab to a nasal sponge. We performed a multicenter\u00a0study, on 124 adults and children, in a point\u2010of\u2010care setting. Sensitivity, specificity and overall acceptance of the COVID\u2010VIRO ALL IN\u00ae self\u2010test compared to\u00a0reverse transcriptase polymerase chain reaction (RT\u2010PCR) on nasopharyngeal samples were of 93.0%, 100%, and 97.5%, respectively. We then performed a multicenter, usability study to evaluate the ease of use of COVID\u2010VIRO ALL IN\u00ae on 68 laypersons adults. A vast majority of participants correctly executed and interpreted the test. The usability was then specifically investigated on 40 children and teenagers, comparing COVID\u2010VIRO\u00ae first generation to the new COVID\u2010VIRO ALL IN\u00ae. They all found COVID\u2010VIRO ALL IN\u00ae more comfortable and easier to use. For young children, the new self\u2010test seems safer (less risk of trauma and no liquid exposure), and faster than saliva\u2010based RT\u2010PCR. Moreover, the COVID\u2010VIRO ALL IN\u00ae can easily be adapted as a multiplex self\u2010test for other respiratory viruses, opening new perspectives of simultaneous, rapid and massive detection of respiratory infections, especially among vulnerable populations like children and elderly people.<\/jats:p>","DOI":"10.1002\/jmv.27812","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:21:29Z","timestamp":1651018889000},"page":"4097-4106","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Evaluation of a new \u201call in one\u201d SARS\u2010CoV\u20102 antigen\u2010detecting rapid diagnostic test and self\u2010test: Diagnostic performance and usability in child and adult populations"],"prefix":"10.1002","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2212-6873","authenticated-orcid":false,"given":"Thierry","family":"Prazuck","sequence":"first","affiliation":[{"name":"Centre gratuit d'information, de d\u00e9pistage et de diagnostic (CeGIDD) Orl\u00e9ans, Centre Hospitalier R\u00e9gional d'Orl\u00e9ans Orl\u00e9ans France"},{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Gravier","sequence":"additional","affiliation":[{"name":"Centre gratuit d'information, de d\u00e9pistage et de diagnostic (CeGIDD) Orl\u00e9ans, Centre Hospitalier R\u00e9gional d'Orl\u00e9ans Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Pires\u2010Roteira","sequence":"additional","affiliation":[{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelie","family":"Theillay","sequence":"additional","affiliation":[{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Pallay","sequence":"additional","affiliation":[{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathilda","family":"Colin","sequence":"additional","affiliation":[{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raphael","family":"Serreau","sequence":"additional","affiliation":[{"name":"Service de m\u00e9decine pr\u00e9ventive Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Hocqueloux","sequence":"additional","affiliation":[{"name":"Centre hospitalier r\u00e9gional d'Orl\u00e9ans, service des maladies infectieuses et tropicales Orl\u00e9ans France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nino Guy","family":"Cassuto","sequence":"additional","affiliation":[{"name":"Laboratoires Drouot Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,25]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization. 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Accessed September 10 2021.https:\/\/www.has-sante.fr\/jcms\/p_3243463\/fr\/covid-19-quelle-place-pour-les-tests-antigeniques-nasaux-dans-la-strategie-de-depistage"},{"key":"e_1_2_9_13_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9. Covid\u201019: Ia has l\u00e8ve la limite d'\u00e2ge pour l'utilisation des tests antig\u00e9niques sur pr\u00e9l\u00e8vement nasal [Internet]. Accessed December 22 2021.\u00a0https:\/\/www.has-sante.fr\/jcms\/p_3263435\/fr\/covid-19-la-has-leve-la-limite-d-age-pour-l-utilisation-des-tests-antigeniques-sur-prelevement-nasal"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27249"},{"key":"e_1_2_9_15_1","unstructured":"Soci\u00e9t\u00e9 Fran\u00e7aise de Microbiologie. 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