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Especially herpesviruses are interesting because their prevalence and persistence in local lymphoid tissue are incompletely known. Our aim was to study herpesvirus and common respiratory virus infections in nonacutely ill adenotonsillar surgery patients. Adenoid and\/or palatine tonsil tissue and nasopharyngeal aspirate (NPA) samples were collected from elective adenoidectomy (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200945) and adenotonsillectomy (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200944) patients (median age: 5, range: 1\u201320). Real\u2010time polymerase chain reaction\u00a0was used to detect 22 distinct viruses from collected samples. The overall prevalence of herpesviruses was 89% and respiratory viruses 94%. Human herpesviruses 6 (HHV6), 7 (HHV7), and Epstein\u2013Barr virus (EBV) were found, respectively, in adenoids (33%, 26%, 25%), tonsils (45%, 52%, 23%), and NPA (46%, 38%, 25%). Copy numbers of the HHV6 and HHV7 genome were significantly higher in tonsils than in adenoids. Patients with intra\u2010adenoid HHV6 were younger than those without. Detection rates of EBV and HHV7 showed agreement between corresponding sample types. This study shows that adenoid and tonsil tissues commonly harbor human herpes\u2010 and respiratory viruses, and it shows the differences in virus findings between sample types.\n                  <\/jats:p>","DOI":"10.1002\/jmv.27818","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T23:33:36Z","timestamp":1651275216000},"page":"4470-4477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Herpesvirus infections in adenoids in patients with chronic adenotonsillar disease"],"prefix":"10.1002","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0169-2681","authenticated-orcid":false,"given":"Lotta E.","family":"Ivaska","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Turku University Hospital University of Turku Turku 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