{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:56Z","timestamp":1786978196875,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,10]],"date-time":"2022-09-10T00:00:00Z","timestamp":1662768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,9,10]],"date-time":"2022-09-10T00:00:00Z","timestamp":1662768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In 2019, an outbreak of pharyngoconjunctival fever (PCF) occurred at a swimming center in Zhejiang Province, China. A total of 97 (13.55%) of the 716 amateur swimmers had illnesses, with 24 patients (24.74%) hospitalized in the pediatric ward. Human adenovirus serotype 7 (HAdV\u20107) was isolated from one concentrated water from the swimming pool, and 20 of 97 positive cases without liver damage. This outbreak led to a nosocomial outbreak in the pediatric ward, in which 1\u00a0nurse had a fever and was confirmed to be adenovirus positive. The hexon, fiber, and penton genes from 20 outbreak cases, 1\u00a0water sample, and 1\u00a0nurse had 100% homology. Furthermore, 2\u00a0cases admitted to the pediatric ward, 2\u00a0parents, and 1\u00a0doctor were confirmed to be human coronaviruses (HCoV\u2010229E) positive. Finally, all outbreak cases had fully recovered, regardless of a single infection (adenovirus or HCoV\u2010229E) or coinfection of these two viruses simultaneously. Thus, PCF and acute respiratory disease outbreaks in Zhejiang were caused by the completely homologous type 7 adenovirus and HCoV\u2010229E, respectively. The swimming pool water contaminated with HAdV\u20107 was most likely the source of the PCF outbreak, whereas nosocomial transmission might be the source of HCoV\u2010229E outbreak.<\/jats:p>","DOI":"10.1002\/jmv.28101","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T00:34:48Z","timestamp":1661733288000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Outbreak of acute respiratory disease caused by human adenovirus type 7 and human coronavirus\u2010229E in Zhejiang Province, China"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2053-0941","authenticated-orcid":false,"given":"Shelan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang 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