{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:15:30Z","timestamp":1789398930947,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["YNWR\u2010YLXZ\u20102019\u2010008"],"award-info":[{"award-number":["YNWR\u2010YLXZ\u20102019\u2010008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005273","name":"Natural Science Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["2021\u2010I2M\u20101\u2010036"],"award-info":[{"award-number":["2021\u2010I2M\u20101\u2010036"]}],"id":[{"id":"10.13039\/501100005273","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In 2019, a serious dengue virus (DENV) infection broke out in the Xishuangbanna Dai Autonomous Prefecture, China. Therefore, we conducted a molecular epidemiological analysis in people that contracted DENV serotype 1\u00a0(DENV\u20101) during this year. We analyzed the molecular epidemiology of six DENV\u20101 epidemic strains in 2019 by full\u2010length genome sequencing, amino acid mutation site analysis, evolutionary tree analysis, and recombination site comparison analysis. Through the analysis of amino acid mutation sites, it was found that DENV\u20101 strain (MW386867) was different from the other five epidemic DENV\u20101 strains in Xishuangbanna in 2019. MW386867 had unique mutation sites at six loci. The six epidemic DENV\u20101 strains in Xishuangbanna in 2019 were divided into two clusters. MW386867 was highly similar to the MG679800 (Myanmar 2017), MG679801 (Myanmar 2017), and KC172834 (Laos 2008), and the other five strains were highly similar to JQ045660 (Vietnam 2011), FJ176780 (GuangDong 2006). Genetic recombination analysis revealed that there was no recombination signal in the six epidemic DENV\u20101 strains in Xishuangbanna in 2019. We speculate that the\u00a0DENV\u20101 epidemic in 2019 has a co\u2010epidemic of local strains and cross\u2010border strains.<\/jats:p>","DOI":"10.1002\/jmv.28115","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T03:24:43Z","timestamp":1662348283000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The whole\u2010genome sequencing of prevalent DENV\u20101 strains during the largest dengue virus outbreak in Xishuangbanna Dai autonomous prefecture in 2019"],"prefix":"10.1002","volume":"95","author":[{"given":"Daiying","family":"Li","sequence":"first","affiliation":[{"name":"Institute of Medical Biology Chinese Academy of Medical Sciences, and Peking Union Medical College Kunming People's Republic of China"},{"name":"Yunnan Key Laboratory of Vaccine Research &amp; Development on Severe Infectious Diseases Kunming People's Republic of China"},{"name":"Yunnan Key Laboratory of Vector\u2010Borne Infectious Disease Kunming People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MingWang","family":"Long","sequence":"additional","affiliation":[{"name":"Institute of Medical Biology Chinese Academy of Medical Sciences, and Peking Union Medical College Kunming People's Republic of China"},{"name":"Yunnan Key Laboratory of Vaccine Research &amp; 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