{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:00:27Z","timestamp":1787313627166,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With increased transmissibility and novel transmission mode, monkeypox poses new threats to public health globally in the background of the ongoing COVID\u201019 pandemic. Estimates of the serial interval, a key epidemiological parameter of infectious disease transmission, could provide insights into the virus transmission risks. As of October 2022, little was known about the serial interval of monkeypox due to the lack of contact tracing data. In this study, public\u2010available contact tracing data of global monkeypox cases were collected and 21 infector\u2010infectee transmission pairs were identified. We proposed a statistical method applied to real\u2010world observations to estimate the serial interval of the monkeypox. We estimated a mean serial interval of 5.6 days with the right truncation and sampling bias adjusted\u00a0and calculated the reproduction number of 1.33 for the early monkeypox outbreaks at a global scale. Our findings\u00a0provided a preliminary understanding of the transmission potentials of the current situation of monkeypox outbreaks. We highlighted the need\u00a0for continuous surveillance of monkeypox for transmission risk assessment.<\/jats:p>","DOI":"10.1002\/jmv.28248","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T23:38:46Z","timestamp":1666395526000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Estimation of the serial interval of monkeypox during the early outbreak in 2022"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9002-0483","authenticated-orcid":false,"given":"Zihao","family":"Guo","sequence":"first","affiliation":[{"name":"JC School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8722-6149","authenticated-orcid":false,"given":"Shi","family":"Zhao","sequence":"additional","affiliation":[{"name":"JC School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengzhi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3253-654X","authenticated-orcid":false,"given":"Daihai","family":"He","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics Hong Kong Polytechnic University Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka Chun","family":"Chong","sequence":"additional","affiliation":[{"name":"JC School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"},{"name":"Centre for Health Systems and Policy Research, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eng Kiong","family":"Yeoh","sequence":"additional","affiliation":[{"name":"JC School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"},{"name":"Centre for Health Systems and Policy Research, Faculty of Medicine Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27902"},{"key":"e_1_2_9_3_1","unstructured":"Who.int.\u00a0WHO Director\u2010General declares the ongoing monkeypox outbreak a Public Health Emergency of International Concern. 2022. Accessed October 1 2022.\u00a0https:\/\/www.who.int\/europe\/news\/item\/23-07-2022-who-director-general-declares-the-ongoing-monkeypox-outbreak-a-public-health-event-of-international-concern"},{"key":"e_1_2_9_4_1","unstructured":"Who.int.\u00a0Multi\u2010country outbreak of monkeypox external situation report #5\u20147 September 2022.\u00a0 Accessed October 1 2022.https:\/\/www.who.int\/publications\/m\/item\/multi-country-outbreak-of-monkeypox--external-situation-report--5---7-september-2022"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.24.2200448"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2011548118"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0218348X22400230"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0063050"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0218348X22400175"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3934\/mbe.2022633"},{"key":"e_1_2_9_11_1","article-title":"With monkeypox spreading globally, many experts believe the virus can't be contained","author":"Branswell H","year":"2022","journal-title":"Stat"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00359-0"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.17.2000257"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.epidem.2021.100482"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.02.060"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphy.2020.00347"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2006.3754"},{"key":"e_1_2_9_18_1","unstructured":"Investigation into monkeypox outbreak in England: technical briefing 1. 2020.\u00a0https:\/\/www.gov.uk\/government\/publications\/monkeypox-outbreak-technical-briefings\/investigation-into-monkeypox-outbreak-in-england-technical-briefing-1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2015.2026"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc9004"},{"key":"e_1_2_9_21_1","article-title":"Reproduction number of monkeypox in the early stage of the 2022 multi\u2010country outbreak","author":"Du Z","year":"2022","journal-title":"J Travel Med"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.28248","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.28248","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.28248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:47:12Z","timestamp":1772959632000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.28248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,3]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1002\/jmv.28248"],"URL":"https:\/\/doi.org\/10.1002\/jmv.28248","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,3]]},"assertion":[{"value":"2022-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e28248"}}