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Both genotypes represent examples of intertypic recombination. Genotype D109 is most closely related to genotype D56 (97.68% genomic similarity) and features a type D22\u2010like penton base, a type D19\u2010like hexon gene, and a type D9\u2010like fiber [P22\/H19\/F9]. On the other hand, genotype D110 is most closely related to type D22 (96.94% genomic similarity) and features a type D67\u2010like penton base, a novel hexon gene, and a type D9\u2010like fiber [P67\/H110\/F9]. Importantly, the fibers of both novel genotypes are highly similar to those of genotypes D56 and D59, which have also been isolated from a few cases of respiratory infections. The present report shows data contributing to the understanding of the molecular determinants of the expanded tissue tropism of certain members of species HAdV\u2010D.<\/jats:p>","DOI":"10.1002\/jmv.28653","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T13:24:27Z","timestamp":1678454667000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Two novel recombinant human mastadenovirus D genotypes associated with acute respiratory illness"],"prefix":"10.1002","volume":"95","author":[{"given":"Gabriel","family":"Gonzalez","sequence":"first","affiliation":[{"name":"UCD National Virus Reference Laboratory  Dublin Ireland"},{"name":"Japan Initiative for World\u2010leading Vaccine Research and Development Centers Hokkaido University, Institute for Vaccine Research and Development  Hokkaido 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