{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:18:10Z","timestamp":1791429490748,"version":"4.3.3"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The long\u2010term risk of herpes zoster (HZ) after recovery from a SARS\u2010CoV\u20102 infection is unclear. This retrospective cohort study assessed the risk of HZ in patients following a COVID\u201019 diagnosis. This retrospective, propensity score\u2010matched cohort study was based on the multi\u2010institutional research network TriNetX. The risk of incident HZ in patients with COVID\u201019 was compared with that of those not infected with SARS\u2010CoV\u20102 during a 1\u2010year follow\u2010up period. Hazard ratios (HRs) and 95% confidence intervals (CIs) of HZ and its subtypes were calculated. This study identified 1\u2009221\u2009343 patients with and without COVID\u201019 diagnoses with matched baseline characteristics. During the 1\u2010year follow\u2010up period, patients with COVID\u201019 had a higher risk of HZ compared with those without COVID\u201019 (HR: 1.59; 95% CI: 1.49\u20131.69). In addition, compared with the control group patients, those with COVID\u201019 had a higher risk of HZ ophthalmicus (HR: 1.31; 95% CI: 1.01\u20131.71), disseminated zoster (HR: 2.80; 95% CI: 1.37\u20135.74), zoster with other complications (HR: 1.46; 95% CI: 1.18\u20131.79), and zoster without complications (HR: 1.66; 95% CI: 1.55\u20131.77). Kaplan\u2013Meier curve analysis (log\u2010rank\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) results indicated that the risk of HZ remained significantly higher in patients with COVID\u201019 compared with those without COVID\u201019. Finally, the higher risk of HZ in the COVID\u201019 cohort compared with that in the non\u2010COVID\u201019 cohort remained consistent across subgroup analyses regardless of vaccine status, age, or sex. The risk of HZ within a 12\u2010month follow\u2010up period was significantly higher in patients who had recovered from COVID\u201019 compared with that in the control group. This result highlights the importance of carefully monitoring HZ in this population and suggests the potential benefit of the HZ vaccine for patients with COVID\u201019.\n                  <\/jats:p>","DOI":"10.1002\/jmv.28745","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T08:07:38Z","timestamp":1681805258000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Long\u2010term risk of herpes zoster following COVID\u201019: A retrospective cohort study of 2\u2009442\u2009686 patients"],"prefix":"10.1002","volume":"95","author":[{"given":"Yi\u2010Chen","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung\u2010Han","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Medical Research Chi Mei Medical Center Tainan Taiwan"},{"name":"Department of Information Management Southern Taiwan University of Science and Technology Tainan Taiwan"},{"name":"Cancer Center, Wan Fang Hospital Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting\u2010Hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Chi Mei Medical Center Tainan City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3290-1909","authenticated-orcid":false,"given":"Jheng\u2010Yan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Nutrition Chi Mei Medical Center Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8682-1322","authenticated-orcid":false,"given":"Po\u2010Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4630-3923","authenticated-orcid":false,"given":"Ya\u2010Wen","family":"Tsai","sequence":"additional","affiliation":[{"name":"Center for Integrative Medicine Chi Mei Medical Center Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6334-2388","authenticated-orcid":false,"given":"Chih\u2010Cheng","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Hospital Medicine, Department of Internal Medicine Chi Mei Medical Center Tainan Taiwan"},{"name":"School of Medicine National Sun Yat\u2010sen University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.105924"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.105946"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2009249"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2009575"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2020.02.012"},{"key":"e_1_2_8_7_1","unstructured":"World Health Organization. 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