{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T15:31:22Z","timestamp":1774539082456,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010653","name":"Masarykova Univerzita","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The recent reports of oral side effects (SEs) following COVID\u201019 vaccination warrant further investigation into their prevalence, severity, and aetiology. This study was conducted to synthesize the first\u2010ever population\u2010level evidence about oral SEs of COVID\u201019 vaccines in Europe. The European Union Drug Regulating Authorities Pharmacovigilance (EudraVigilance) database was accessed in August 2022 to extract summary data of all potential oral SEs reported after COVID\u201019 vaccination. The data were reported descriptively and cross\u2010tabulated to facilitate sub\u2010group analysis per vaccine type, sex, and age group. Dysgeusia was the most commonly reported oral SE (0.381 case per each 100 received reports), followed by oral paraesthesia (0.315%), ageusia (0.296%), lip swelling (0.243%), dry mouth (0.215%), oral hypoaesthesia (0.210%), swollen tongue (0.207%), and taste disorder (0.173%). Females had significantly (<jats:italic>Sig<\/jats:italic>.\u2009&lt;\u20090.001) a higher prevalence of all most common (top 20) oral SEs, except for salivary hypersecretion, which was equally prevalent among females and males. The present study revealed a low prevalence of oral SEs, with taste\u2010related, other sensory and anaphylactic SEs being the most common SEs in Europe, similar to what was found earlier among the US population. Future studies should explore the potential risk factors of oral sensory and anaphylactic SEs to verify whether they are causally linked to COVID\u201019 vaccines.<\/jats:p>","DOI":"10.1002\/jmv.28771","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T14:20:13Z","timestamp":1683728413000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Oral side effects of COVID\u201019 vaccines in 32 European countries: Analysis of EudraVigilance reports"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5918-8966","authenticated-orcid":false,"given":"Abanoub","family":"Riad","sequence":"first","affiliation":[{"name":"Department of Public Health Faculty of Medicine, Masaryk University Brno Czech Republic"},{"name":"Department of Oral and Maxillofacial Surgery Justus\u2010Liebig\u2010University Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelly","family":"Schulz\u2010Weidner","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry Justus\u2010Liebig\u2010University Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arkadiusz","family":"Dziedzic","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry with Endodontics Medical University of Silesia Katowice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans\u2010Peter","family":"Howaldt","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Justus\u2010Liebig\u2010University Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameh","family":"Attia","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Justus\u2010Liebig\u2010University Giessen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345211029637"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820934380"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13359"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.20396\/bjos.v19i0.8661354"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14479"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040581"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2609.202059"},{"key":"e_1_2_10_9_1","article-title":"Angular cheilitis of COVID\u201019 patients: a case\u2010series and literature review","author":"Riad A","year":"2020","journal-title":"Oral Dis"},{"key":"e_1_2_10_10_1","unstructured":"World Health Organization (WHO).A Brief History of Vaccination.History of Vaccination. 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