{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:19:42Z","timestamp":1788347982630,"version":"build-2803163510"},"reference-count":57,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The 2022 annual meeting of the HTLV &amp; HIV\u20102 Spanish Network was held in Madrid on December 14. We summarize here the main information presented and discussed at the workshop and review time trends for human retroviral infections in Spain. As transmissible agents, infections by human retroviruses are of obligatory declaration. Until the end of 2022, the Spanish national registry had recorded 451 cases of HTLV\u20101, 821 of HTLV\u20102, and 416 of HIV\u20102. For HIV\u20101, estimates are of 150\u2009000 people currently living with HIV\u20101 and 60\u2009000 cumulative deaths due to AIDS. During year 2022, new diagnoses in Spain were of 22 for HTLV\u20101, 6 for HTLV\u20102, and 7 for HIV\u20102. The last updated figures for HIV\u20101 are from 2021 and counted 2786 new diagnoses. The slowdown in yearly infections for HIV\u20101 in Spain points out that new strategies are needed to achieve the United Nations 95\u201095\u201095 targets by 2025. For the remaining neglected human retroviral infections, their control might be pushed throughout four interventions: (1) expanding testing; (2) improving education and interventions aimed to reduce risk behaviors; (3) facilitating access to antiretrovirals as treatment and prevention, including further development of long\u2010acting formulations; and (4) increasing vaccine research efforts. Spain is a 47 million population country in South Europe with strong migration flows from HTLV\u20101 endemic regions in Latin America and Sub\u2010Saharan Africa. At this time universal HTLV screening has been implemented only in the transplantation setting, following the report of 5 cases of HTLV\u2010associated myelopathy shortly after transplantation of organs from HTLV\u20101 positive donors. There are four target populations for expanding testing and unveiling asymptomatic carriers responsible for silent HTLV\u20101 transmissions: (1) migrants; (2) individuals with sexually transmitted infections; (3) pregnant women; and (4) blood donors.<\/jats:p>","DOI":"10.1002\/jmv.28779","type":"journal-article","created":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T06:54:48Z","timestamp":1683615288000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The slowdown of new infections by human retroviruses has reached a plateau in Spain"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5224-7492","authenticated-orcid":false,"given":"Carmen","family":"de Mendoza","sequence":"first","affiliation":[{"name":"Puerta de Hierro University Hospital &amp; Research Foundation\u2010IDIPHISA Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Carrizo","sequence":"additional","affiliation":[{"name":"Puerta de Hierro University Hospital &amp; 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