{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:18Z","timestamp":1786978098018,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In May 2022, several countries reported mpox cases from patients without history of traveling to endemic areas. France was one of the most affected European countries by this outbreak. In this study, the clinical characteristics of mpox cases in France were described, and the genetic diversity of the virus was studied. Patients diagnosed with mpox infection (quantitative polymerase chain reaction\n                    <jats:italic>c<\/jats:italic>\n                    <jats:sub>t<\/jats:sub>\n                    \u2009&lt;\u200928) between May 21, and July 4, 2022 and between 16th August and 10th September 2022 were included to this study. Twelve amplicons corresponding to the most polymorphic regions of the mpox genome and covering ~30\u2009000 nucleotides were generated and sequenced using the S5 XL Ion Torrent technology to evaluate the genetic diversity of mpox sequences. One hundred and forty\u2010eight patients were diagnosed with mpox\u2010infection. 95% were men, 5% transgender (M\u2010to\u2010F), 50% were taking human immunodeficiency virus (HIV) pre\u2010exposure prophylaxis, and 25% were HIV seropositive. One hundred and sixty\u2010two samples (some patients had two samples) were sequenced and compared to GenBank sequences. Overall, low genetic diversity of mpox sequences was found compared with pre\u2010epidemic Western\u2010African sequences, with 32 distinct mutational patterns. This study provides a first glance at the mutational landscape of early mpox 2022 circulating strains in Paris (France).\n                  <\/jats:p>","DOI":"10.1002\/jmv.28853","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T05:40:15Z","timestamp":1686202815000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Genomic diversity of mpox virus in Paris area (France) during the 2022 outbreak"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5023-855X","authenticated-orcid":false,"given":"G\u00e9raldine","family":"Piorkowski","sequence":"first","affiliation":[{"name":"Unit\u00e9 des Virus \u00c9mergents (UVE: Aix\u2010Marseille Universit\u00e9\u2010IRD_190\u2010Inserm_1207) Marseille 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2196-6141","authenticated-orcid":false,"given":"Valentine Marie","family":"Ferr\u00e9","sequence":"additional","affiliation":[{"name":"Inserm, UMR1137, IAME, Service de Virologie, AP\u2010HP, H\u00f4pital Bichat\u2010Claude Bernard Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadhira","family":"Houhou\u2010Fidouh","sequence":"additional","affiliation":[{"name":"Inserm, UMR1137, IAME, Service de Virologie, AP\u2010HP, H\u00f4pital Bichat\u2010Claude Bernard Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazdan","family":"Yazdanpanah","sequence":"additional","affiliation":[{"name":"Inserm, UMR1137, IAME, Service des Maladies Infectieuses et Tropicales, AP\u2010HP, H\u00f4pital Bichat\u2010Claude Bernard Universit\u00e9 Paris Cit\u00e9  Paris France"},{"name":"Agence nationale de Recherche sur le SIDA et les h\u00e9patites virales, Maladies Infectieuses \u00e9mergentes  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quentin","family":"Le Hingrat","sequence":"additional","affiliation":[{"name":"Inserm, UMR1137, IAME, Service de Virologie, AP\u2010HP, H\u00f4pital Bichat\u2010Claude Bernard Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Raoul","sequence":"additional","affiliation":[{"name":"Agence nationale de Recherche sur le SIDA et les h\u00e9patites virales, Maladies Infectieuses \u00e9mergentes  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Charpentier","sequence":"additional","affiliation":[{"name":"Inserm, UMR1137, IAME, Service de Virologie, AP\u2010HP, H\u00f4pital Bichat\u2010Claude Bernard Universit\u00e9 Paris Cit\u00e9  Paris 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