{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:57:37Z","timestamp":1753869457429,"version":"3.41.2"},"reference-count":7,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A man in his mid\u201030s presented with 1 week of painful, progressive, and confluent tongue and chin ulcerations. Swabs of the lesions were detected positive for monkeypox (mpox) DNA by polymerase chain reaction. During hospitalization, he received a diagnosis of human immunodeficiency virus\u20101. Due to severe oral pain, the patient was treated with intravenous tecovirimat 200\u2009mg every 12\u2009h for 4 days with remarkable improvement in lingual lesions. He completed a total 14\u2010day course with oral tecovirimat. Our patient's clinical progress contributes to the data available for the potential efficacy of intravenous tecovirimat for mpox infection in humans.<\/jats:p>","DOI":"10.1002\/jmv.29078","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T12:25:44Z","timestamp":1693830344000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intravenous tecovirimat treatment of oral monkeypox lesions in a patient with HIV\u20101"],"prefix":"10.1002","volume":"95","author":[{"given":"Wan Hsiang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1760-4383","authenticated-orcid":false,"given":"Dierdre B.","family":"Axell\u2010House","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine Houston Methodist Hospital Houston Texas USA"},{"name":"Center for Infectious Diseases Research Houston Methodist Research Institute Houston Texas USA"},{"name":"Department of Medicine Weill Cornell Medical College New York City New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2208860"},{"key":"e_1_2_6_3_1","unstructured":"Centers for Disease Control and Prevention.2023. Guidance for Tecovirimat Use. Accessed May 20 2023.https:\/\/www.cdc.gov\/poxvirus\/mpox\/clinicians\/Tecovirimat.html"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2210125"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7137e1"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28825"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28868"},{"key":"e_1_2_6_8_1","unstructured":"National Institute of Allergy and Infectious Diseases.2023. Study of Tecovirimat for Human Monkeypox Virus (STOMP). Accessed May 20 2023.https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05534984"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.29078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T13:56:17Z","timestamp":1695822977000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.29078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":7,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/jmv.29078"],"URL":"https:\/\/doi.org\/10.1002\/jmv.29078","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"type":"print","value":"0146-6615"},{"type":"electronic","value":"1096-9071"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"2023-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e29078"}}