{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:51:58Z","timestamp":1788375118660,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T00:00:00Z","timestamp":1696723200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19AI68621"],"award-info":[{"award-number":["U19AI68621"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In 2022 the World Health Organization declared a Public Health Emergency for an outbreak of mpox, the zoonotic Orthopoxvirus (OPV) affecting at least 104 nonendemic locations worldwide. Serologic detection of mpox infection is problematic, however, due to considerable antigenic and serologic cross\u2010reactivity among OPVs and smallpox\u2010vaccinated individuals. In this report, we developed a high\u2010throughput multiplex microsphere immunoassay using a combination of mpox\u2010specific peptides and cross\u2010reactive OPV proteins that results in the specific serologic detection of mpox infection with 93% sensitivity and 98% specificity. The New York State Non\u2010Vaccinia Orthopoxvirus Microsphere Immunoassay is an important tool to detect subclinical mpox infection and understand the extent of mpox spread in the community through retrospective analysis.<\/jats:p>","DOI":"10.1002\/jmv.29134","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T08:45:44Z","timestamp":1696927544000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Development of a novel serological assay for the detection of mpox infection in vaccinated populations"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8841-9401","authenticated-orcid":false,"given":"Jennifer L.","family":"Yates","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center New York State Department of Health  Albany New York USA"},{"name":"Department of Biomedical Sciences The School of Public Heath, The University at Albany  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle T.","family":"Hunt","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center New York State Department of Health  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen E.","family":"Kulas","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center New York State Department of Health  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen J.","family":"Chave","sequence":"additional","affiliation":[{"name":"Scientific Cores, Wadsworth Center New York State Department of Health  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Styer","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Wadsworth Center New York State Department of Health  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