{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:13:12Z","timestamp":1787317992912,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Since May 2022, over 91\u2009000 cases of mpox have been reported globally with the majority of cases occurring among adult males who identify as gay, bisexual, or men who have sex with men (gbMSM). Given the rapid emergence of the global mpox outbreak, many public health authorities did not have established mpox outbreak control indicators or criteria for declaring an mpox outbreak over. Expert consensus in Ontario, Canada, set thresholds for five key indicators of mpox outbreak control as follows: estimated number of currently infectious cases\u2009&lt;\u20095; effective reproductive number\u2009&lt;\u20091.0; doubling time\u2009&gt;\u200942 days; weekly test positivity\u2009&lt;\u20095%; and sporadic non\u2010gbMSM cases (i.e., female and pediatric cases). Once all indicators were achieved, a 52\u2010day period based on two incubation periods for mpox and a 10\u2010day reporting delay was employed to monitor for indicator stability. After all five indicators remained at expected levels, the mpox outbreak in Ontario was declared over on December 10, 2022. Despite current low levels of mpox activity globally, some jurisdictions may benefit from utilizing or modifying these outbreak control indicators during a future localized mpox outbreak.<\/jats:p>","DOI":"10.1002\/jmv.29251","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T12:54:31Z","timestamp":1701867271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Mpox outbreak control indicators used in Ontario, Canada: May 21\u2013December 10, 2022"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4219-6887","authenticated-orcid":false,"given":"Austin","family":"Zygmunt","sequence":"first","affiliation":[{"name":"Public Health Ontario  Toronto ON Canada"},{"name":"Department of Family Medicine University of Ottawa  Ottawa ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Saunders","sequence":"additional","affiliation":[{"name":"Public Health Ontario  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Navarro","sequence":"additional","affiliation":[{"name":"Public Health Ontario  Toronto ON Canada"},{"name":"Clinical Public Health Division Dalla Lana School of Public Health, University of Toronto  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maan","family":"Hasso","sequence":"additional","affiliation":[{"name":"Public Health Ontario  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Collinson","sequence":"additional","affiliation":[{"name":"Public Health Ontario  Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,6]]},"reference":[{"key":"e_1_2_12_2_1","volume-title":"Mpox (Monkeypox) Epidemiology Update","author":"Health Infobase","year":"2023"},{"key":"e_1_2_12_3_1","volume-title":"2022\u201023 Mpox (Monkeypox) Outbreak: Global Trends. Detailed Case Data","author":"World Health Organization (WHO)","year":"2023"},{"key":"e_1_2_12_4_1","volume-title":"Research and analysis: Mpox (monkeypox) outbreak: epidemiological overview, 1 June 2023","author":"UK Health Security Agency","year":"2023"},{"key":"e_1_2_12_5_1","volume-title":"Mpox: Assessment 2","author":"Centers for Disease Control and Prevention (CDC)","year":"2023"},{"key":"e_1_2_12_6_1","volume-title":"Proposal for Deactivating the OICC and Declaring the Outbreak Over \u2010 Outbreak Toolkit","author":"National Collaborating Centre for Infectious Diseases (NCCID); National Collaborating Centre for Environmental Health (NCCEH)","year":"2022"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28270"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-022-02725-2"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43088-022-00316-x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0290387"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11020468"},{"key":"e_1_2_12_12_1","volume-title":"Ontario Public Health System: Public Health History","author":"Ontario Agency for Health Protection and Promotion (Public Health Ontario)","year":"2020"},{"key":"e_1_2_12_13_1","volume-title":"Recommendations for the Management of Cases and Contacts of mpox in Ontario","author":"Ontario Ministry of Health","year":"2023"},{"key":"e_1_2_12_14_1","volume-title":"Reproduction Number (R) and Growth Rate (r) of the COVID\u201019 Epidemic in the UK: Methods of Estimation, Data Sources, Causes of Heterogeneity, and Use as a Guide in Policy Formulation","author":"Royal Society","year":"2020"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2608.200219"},{"key":"e_1_2_12_16_1","volume-title":"COVID\u201019 Testing: Understanding the \u201cPercent Positive\u201d","author":"Dowdy D","year":"2020"},{"key":"e_1_2_12_17_1","volume-title":"Monkeypox Virus: Test Methods","author":"Ontario Agency for Health Protection and Promotion (Public Health Ontario)","year":"2022"},{"key":"e_1_2_12_18_1","volume-title":"Multi\u2010Country Monkeypox Outbreak: Situation Update","author":"World Health Organization (WHO)","year":"2022"},{"key":"e_1_2_12_19_1","first-page":"23","volume-title":"The Principles of Disease Elimination and Eradication","author":"Dowdle WR","year":"1999"},{"key":"e_1_2_12_20_1","volume-title":"Mpox Immunization and Post\u2010Immunization Cases in Ontario. 1st Revision","author":"Ontario Agency for Health Protection and Promotion (Public Health Ontario)","year":"2023"},{"key":"e_1_2_12_21_1","unstructured":"Public Health Agency of Canada; National Advisory Committee of Immunization (NACI).NACI Rapid Response: Interim Guidance on the Use of Imvamune in the Context of Monkeypox Outbreaks in Canada. Her Majesty the Queen in Right of Canada as represented by the Minister of Health;2022.https:\/\/www.canada.ca\/en\/public-health\/services\/immunization\/national-advisory-committee-on-immunization-naci\/guidance-imvamune-monkeypox.html"},{"key":"e_1_2_12_22_1","first-page":"1","volume-title":"Green Book","author":"United Kingdom Health Security Agency","year":"2022"},{"key":"e_1_2_12_23_1","volume-title":"Mpox Vaccine (Imvamune\u00ae) Guidance for Health Care Providers. Version 3.2","author":"Ontario Ministry of Health","year":"2023"},{"key":"e_1_2_12_24_1","article-title":"Effectiveness of one dose of MVA\u2010BN vaccine against mpox infection in males in Ontario, Canada: a target trial emulation","author":"Navarro C","year":"2023","journal-title":"medRxiv"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38816-8"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.29251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T11:05:35Z","timestamp":1714993535000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.29251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":24,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1002\/jmv.29251"],"URL":"https:\/\/doi.org\/10.1002\/jmv.29251","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"2023-08-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e29251"}}