{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:43:37Z","timestamp":1790934217448,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>After the introduction of the rotavirus vaccine into the Universal Immunization Program in India in 2016, relatively few studies have assessed the prevalence and epidemiological patterns of acute gastroenteritis (AGE) among hospitalized children \u22645 years of age. We used a uniform protocol to recruit children with AGE as well as standardized testing and typing protocols. Stool specimens from children with AGE younger than 5 years of age admitted to six hospitals in three cities in India were collected from January 2017 through December 2019. Norovirus was detected by real\u2010time reverse transcription\u2010polymerase chain reaction (RT\u2010qPCR) followed by typing positive specimens by conventional RT\u2010PCR and Sanger sequencing. Norovirus was detected in 322 (14.8%) of 2182 specimens with the highest rate in 2018 (17.6%, 146\/829), followed by 2019 (14.4%, 122\/849)\u00a0and 2017 (10.7%, 54\/504). Rotavirus vaccine status was known for 91.6% of the children of which 70.4% were vaccinated and 29.6% not. Norovirus positivity in rotavirus\u2010vaccinated children was 16.3% and 12% in unvaccinated children. GII.4 Sydney[P16] (39.3%), GII.4 Sydney[P31] (18.7%), GII.2[P16] (10%), GI.3[P13] (6.8%), GII.3[P16] (5.9%), and GII.13[P16] (5%) accounted for 85.8% (188\/219) of the typed strains. Our data highlight the importance of norovirus in Indian children hospitalized with AGE.<\/jats:p>","DOI":"10.1002\/jmv.29384","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T15:11:15Z","timestamp":1705590675000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Hospital\u2010based norovirus surveillance in children &lt;5 years of age from 2017 to 2019 in India"],"prefix":"10.1002","volume":"96","author":[{"given":"Sidhartha","family":"Giri","sequence":"first","affiliation":[{"name":"Division of Gastrointestinal Sciences Christian Medical College  Vellore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Chhabra","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruta","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Interactive Research School for Health Affairs (IRSHA) Bharati Vidyapeeth  Pune India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhabharathi","family":"Reju","sequence":"additional","affiliation":[{"name":"Department of Microbiology Sri Ramachandra Institute of Higher Education and Research (SRIHER)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satheesh Kumar","family":"Sabapathy","sequence":"additional","affiliation":[{"name":"Indian Council of Medical Research (ICMR)\u2010National Institute of Epidemiology (NIE)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6480-5703","authenticated-orcid":false,"given":"Sribal","family":"Selvarajan","sequence":"additional","affiliation":[{"name":"Department of Microbiology Sri Ramachandra Institute of Higher Education and Research (SRIHER)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tintu","family":"Varghese","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Sciences Christian Medical College  Vellore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maheshwari","family":"Kalaivanan","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Sciences Christian Medical College  Vellore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyadharishini","family":"Dorairaj","sequence":"additional","affiliation":[{"name":"Institute of Child Health and Hospital for Children (ICH)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Kalrao","sequence":"additional","affiliation":[{"name":"Bharati Hospital Bharati Vidyapeeth (Deemed to be University) Medical College  Pune India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Mankar","sequence":"additional","affiliation":[{"name":"Mankar Hospital  Pune India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukund","family":"Sangamnerkar","sequence":"additional","affiliation":[{"name":"Chinmay Hospital  Pune India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish Kumar","family":"Chethrapilly Purushothaman","sequence":"additional","affiliation":[{"name":"Indian Council of Medical Research (ICMR)\u2010National Institute of Epidemiology (NIE)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padma","family":"Srikanth","sequence":"additional","affiliation":[{"name":"Department of Microbiology Sri Ramachandra Institute of Higher Education and Research (SRIHER)  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagandeep","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Sciences Christian Medical College  Vellore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Vinj\u00e9","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,18]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization. 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