{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:02:10Z","timestamp":1787162530333,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008331","name":"Universidade Federal do Rio de Janeiro","doi-asserted-by":"publisher","award":["24864\/2022"],"award-info":[{"award-number":["24864\/2022"]}],"id":[{"id":"10.13039\/501100008331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Mpox is a zoonotic disease historically reported in Africa. Since 2003, limited outbreaks have occurred outside Africa. In 2022, the global spread of cases with sustained interhuman transmission and unusual disease features raised public health concerns. We explore the mpox outbreak in Rio de Janeiro (RJ) state, Brazil, in an observational study of mpox\u2010suspected cases from June to December 2022. Data collection relied on a public healthcare notification form. Diagnosis was determined by MPXV\u2010PCR. In 46 confirmed cases, anti\u2010OPXV IgG was determined by ELISA, and seven MPXV genomes were sequenced. A total of 3095 cases were included, 816 (26.3%) with positive MPXV\u2010PCR results. Most positive cases were men in their 30\u2009s and MSM. A total of 285 (34.9%) MPXV\u2010PCR+ patients live with HIV. Eight were coinfected with varicella\u2010zoster virus. Anogenital lesions and adenomegaly were associated with the diagnosis of mpox. Females and individuals under 18 represented 9.4% and 5.4% of all confirmed cases, respectively, showing higher PCR cycle threshold (Ct) values and fewer anogenital lesions compared to adult men. Anti\u2010OPXV IgG was detected in 29\/46 (63.0%) patients. All analyzed sequences belonged to clade IIb. In RJ state, mpox presented a diverse clinical picture, represented mainly by mild cases with low complication rates and prominent genital involvement. The incidence in females and children was higher than usually reported. The observation of a bimodal distribution of Ct values, with few positive results, may suggest the need to review the diagnostic criteria in these groups.<\/jats:p>","DOI":"10.1002\/jmv.29621","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T03:28:46Z","timestamp":1713929326000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Mpox outbreak in Rio de Janeiro, Brazil: A translational approach"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8577-9313","authenticated-orcid":false,"given":"Guilherme S.","family":"Lira","sequence":"first","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Instituto de Microbiologia Paulo de G\u00f3es Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5339-6323","authenticated-orcid":false,"given":"Victor A.","family":"Ota","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Instituto de Microbiologia Paulo de G\u00f3es Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Q. S.","family":"Melo","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Departamento de Doen\u00e7as Infecciosas e Parasit\u00e1rias, Faculdade de Medicina Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna C. P.","family":"Casti\u00f1eiras","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Hospital Universit\u00e1rio Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela C.","family":"Leit\u00e3o","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Hospital Universit\u00e1rio Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca O.","family":"Silva","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Mariani","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e1ssia C. A.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liane J.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia","family":"Halpern","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thalita F.","family":"Abreu","sequence":"additional","affiliation":[{"name":"Instituto de Puericultura e Pediatria Martag\u00e3o Gesteira Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana A.","family":"Carneiro","sequence":"additional","affiliation":[{"name":"Instituto de Biof\u00edsica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"N\u00facleo Multidisciplinar de Pesquisas em Biologia\u2014NUMPEX\u2010BIO, Campus Duque de Caxias Geraldo Cidade Universidade Federal do Rio de Janeiro Duque de Caxias Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena T.","family":"Scheid","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo A. V.","family":"Souza","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9bora G. M.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e1dia V. G.","family":"Cruz","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Pesquisa e Biodefesa Instituto de Biologia do Ex\u00e9rcito Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Cony","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Central Noel Nutes Secretaria de Estado de Sa\u00fade do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Superintend\u00eancia de Emerg\u00eancias Em Sa\u00fade P\u00fablica, Secretaria de Estado de Sa\u00fade do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loyze P. O.","family":"de Lima","sequence":"additional","affiliation":[{"name":"Centro de Vigil\u00e2ncia Gen\u00f4mica e Avalia\u00e7\u00e3o Sorol\u00f3gica CeVIVAS, Instituto Butantan S\u00e3o Paulo Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent L.","family":"Viala","sequence":"additional","affiliation":[{"name":"Centro de Vigil\u00e2ncia Gen\u00f4mica e Avalia\u00e7\u00e3o Sorol\u00f3gica CeVIVAS, Instituto Butantan S\u00e3o Paulo Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio A.","family":"Caldas","sequence":"additional","affiliation":[{"name":"Instituto de Biof\u00edsica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"N\u00facleo Multidisciplinar de Pesquisas em Biologia\u2014NUMPEX\u2010BIO, Campus Duque de Caxias Geraldo Cidade Universidade Federal do Rio de Janeiro Duque de Caxias Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanderley","family":"de Souza","sequence":"additional","affiliation":[{"name":"Instituto de Biof\u00edsica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Instituto Nacional de Ci\u00eancia e Tecnologia de Biologia Estrutural e Bioimagem (INBEB) and Centro Nacional de Biologia Estrutural e Bioimagem (CENABIO)s Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza M.","family":"Higa","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina M.","family":"Voloch","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Orlando C.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6299-2816","authenticated-orcid":false,"given":"Clarissa R.","family":"Damaso","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Instituto de Biof\u00edsica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael M.","family":"Galliez","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Departamento de Doen\u00e7as Infecciosas e Parasit\u00e1rias, Faculdade de Medicina Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5255-5938","authenticated-orcid":false,"given":"D\u00e9bora S.","family":"Faffe","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Instituto de Biof\u00edsica Carlos Chagas Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9420-6143","authenticated-orcid":false,"given":"Amilcar","family":"Tanuri","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Laborat\u00f3rio de Virologia Molecular, Departamento de Gen\u00e9tica, Instituto de Biologia Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4746-6049","authenticated-orcid":false,"given":"Terezinha M. P. P.","family":"Casti\u00f1eiras","sequence":"additional","affiliation":[{"name":"N\u00facleo de Enfrentamento e Estudos de Doen\u00e7as Infecciosas Emergentes e Reemergentes Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"},{"name":"Departamento de Doen\u00e7as Infecciosas e Parasit\u00e1rias, Faculdade de Medicina Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2022.100424"},{"issue":"5","key":"e_1_2_9_3_1","first-page":"599","article-title":"Isolation and properties of the causal agent of a new variola\u2010like disease (monkeypox) in man","volume":"46","author":"Marennikova SS","year":"1972","journal-title":"Bull World Health Organ"},{"key":"e_1_2_9_4_1","volume-title":"Smallpox and Its Eradication","author":"Fenner F","year":"1988"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.81215-0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007791"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2019.03.001"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6710a5"},{"key":"e_1_2_9_9_1","volume-title":"Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases","author":"Petersen BW","year":"2020"},{"key":"e_1_2_9_10_1","unstructured":"World Health Organization. Multi\u2010country monkeypox outbreak: situation update. Accessed April 26 2023.\u00a0https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON396"},{"key":"e_1_2_9_11_1","unstructured":"eCDC. Factsheet for health professionals on mpox (monkeypox). Accessed April 26 2023.\u00a0https:\/\/www.ecdc.europa.eu\/en\/all-topics-z\/monkeypox\/factsheet-health-professionals"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.21790"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.29147"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-060179"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2023.102578"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005857"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7123e1"},{"key":"e_1_2_9_19_1","article-title":"Shotgun metagenomic sequencing of the first case of monkeypox virus in Brazil, 2022","volume":"64","author":"Claro IM","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"e_1_2_9_20_1","unstructured":"Brasil. Minist\u00e9rio da Sa\u00fade. Boletim Epidemiol\u00f3gico Especial: Mpox n\u00b0 24. Accessed October 16 2023https:\/\/www.gov.br\/saude\/pt-br\/centrais-de-conteudo\/publicacoes\/boletins\/epidemiologicos\/variola-dos-macacos\/boletim-epidemiologico-de-monkeypox-no-24-coe-1\/view"},{"key":"e_1_2_9_21_1","unstructured":"Brasil. Defini\u00e7\u00e3o de caso. Minist\u00e9rio da Sa\u00fade. Accessed April 24 2023.\u00a0https:\/\/www.gov.br\/saude\/pt-br\/composicao\/svsa\/resposta-a-emergencias\/sala-de-situacao-de-saude\/sala-de-situacao-de-monkeypox\/definicao-de-caso"},{"key":"e_1_2_9_22_1","unstructured":"Bio\u2010Manguinhos. Manual do Kit Molecular multiplex OPXV\/MPXV\/VZV\/RP. Accessed October 19 2023.\u00a0https:\/\/www.bio.fiocruz.br\/images\/bm-bul-174-01-r-sn---multiplex--.pdf"},{"key":"e_1_2_9_23_1","unstructured":"Centers for Disease Control and Prevention. Mpox Generic PCR Protocol. Accessed May 4 2023.\u00a0https:\/\/www.cdc.gov\/poxvirus\/mpox\/pdf\/PCR-Diagnostic-Protocol-508.pdf"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15010083"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760230056"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/boc.202000146"},{"key":"e_1_2_9_27_1","unstructured":"Chen*NFG Gagne*L DoucetteM et al. Monkeypox virus multiplexed PCR amplicon sequencing (PrimalSeq) V.2.\u00a0Accessed October 5 2023.\u00a0https:\/\/www.protocols.io\/view\/monkeypox-virus-multiplexed-pcr-amplicon-sequencin-cd8ds9s6"},{"key":"e_1_2_9_28_1","unstructured":"eCDC. Communicable disease threats report 2\u20108 July 2023 week 27. Accessed July 21 2023.\u00a0https:\/\/www.ecdc.europa.eu\/en\/publications-data\/communicable-disease-threats-report-2-8-july-2023-week-27"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7136e1"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2022.102510"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2023.01.045"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2022.100392"},{"key":"e_1_2_9_33_1","article-title":"Ambulatory and hospitalized patients with suspected and confirmed mpox: an observational cohort study from Brazil","volume":"13","author":"Silva MST","year":"2022","journal-title":"The Lancet Regional Health \u2010 Americas"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01436-2"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00273-8"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00333-1"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-02004-w"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00411-X"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2812.221440"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2022.08.012"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02187-0"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.48.2200867"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10393-017-1266-5"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/156.2.293"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005769107"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1309.070175"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7144a4"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-0589"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/v14122800"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.13243"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiad556"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00228-6"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.29621","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:42:02Z","timestamp":1757313722000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.29621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/jmv.29621"],"URL":"https:\/\/doi.org\/10.1002\/jmv.29621","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"2024-02-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e29621"}}