{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:47:52Z","timestamp":1765547272214,"version":"3.41.2"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To investigate the progress of disparities in human immunodeficiency virus\/acquired immunodeficiency syndrome (HIV\/AIDS), gonorrhea, and syphilis among children and adolescents aged 6\u201322 years in China during 2013\u20132021. A total of 614\u2009325 cases data were extracted from the Chinese Information System for Infectious Diseases Control and Prevention during 2013\u20132021. Puberty health education data were drew from the Student Health Surveillance in 2021. Disparity patterns and average annual percentage changes (AAPCs) in sexually transmitted infections (STIs) incidence or new cases in China were examined using descriptive statistics and joinpoint regression. The incidence across 345 cities was stratified by gross domestic product (GDP). Between 2013 and 2021, there were 614\u2009325 reported cases of HIV\/AIDS, gonorrhea, and syphilis among children and adolescents aged 6\u201322, with an annual average incidence of 24.0967 per 100\u2009000. The expansion of HIV\/AIDS has halted, yet the surge in gonorrhea and syphilis remains notably pronounced. The ratio of male to female AIDS incidence increased from 2.75 (2.60, 2.90) to 7.13 (6.68, 7.62), but that of syphilis changed from 0.33 (0.32, 0.34) to 0.56 (0.55, 0.57). Students and out\u2010of\u2010school individuals aged 13\u201315 experienced a notably high increase in STI cases, surpassing other age groups, with an average annual percentage increase of 29.2% and 26.3%, respectively. Nonstudents consistently had a higher incidence rate than students, with an IRR reaching 31.80 (31.24, 32.37) in 2021. A noticeable clustering pattern of new cases emerged in the southeastern region of the Heihe\u2010Tengchong line, extending inland from the coastal areas. Districts and counties with lower rates of puberty sexual health education tended to have higher average STI incidence rates. At the prefecture and city levels, there was a noticeable upward trend on average STI incidence rates in cities with per capita GDPs. Strategies to address those disparities include promoting equitable health education, and widespread sexual health education, particularly in areas with limited access to education and experiencing rapid economic development. The effectiveness of sexual health education intervention needs to be further evaluated in well\u2010designed studies.<\/jats:p>","DOI":"10.1002\/jmv.29808","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T10:48:01Z","timestamp":1721299681000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Improvement and exacerbation of multiple disparities in sexually transmitted infections among children and adolescents aged 6\u201322 years: An analysis of national surveillance data from 2013 to 2021"],"prefix":"10.1002","volume":"96","author":[{"given":"Yi","family":"Zhang","sequence":"first","affiliation":[{"name":"Institute of Child and Adolescent Health, School of Public Health Peking University, National Health Commission Key Laboratory of Reproductive Health Beijing China"},{"name":"UNESCO Chair on Global Health and Education of Peking University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjie","family":"Geng","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Xing","sequence":"additional","affiliation":[{"name":"Institute of Child and Adolescent Health, School of Public Health Peking University, National Health Commission Key Laboratory of Reproductive Health Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Ren","sequence":"additional","affiliation":[{"name":"Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Child and Adolescent Health, School of Public Health Peking University, National Health Commission Key Laboratory of Reproductive Health Beijing 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