{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:20:14Z","timestamp":1788880814889,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To explore the impacts of cytomegalovirus (CMV) infection and antiviral treatment (AVT) on native liver survival (NLS) in biliary atresia (BA) infants. This retrospective cohort study included infants diagnosed as BA between January 2015 and December 2021 at Hunan Children's Hospital. CMV infection was defined by DNA polymerase chain reaction alone (DNA data set) and combination of DNA and immunoglobulin M (CMV data set). In the DNA data set of 330 patients, 234 patients (70.9%) survived with their native liver in 2 years, with 113 (73.9%) in the DNA\u2212 cohort, 70 (65.4%) in the DNA+ and\u00a0AVT\u2212 cohort and 51 (72.9%) in the DNA+ and\u00a0AVT+ cohort, without significant differences by log\u2010rank tests. In patients administrated between 2015 and March 2019, there were 206 evaluable patients in the DNA data set, with rates of 5\u2010year NLS of 68.3% in the DNA\u2212 cohort, similar to that in the DNA+ and\u00a0AVT+ cohort (62.2%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.546), but significantly higher than that in the DNA+ and\u00a0AVT\u2212 cohort (51.4%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.031). Similar trends were also observed in the CMV data set, although statistically insignificant. CMV infection before or on the day of HPE can reduce the rate of 5\u2010year NLS and AVT was recommended for CMV\u2010infected\u00a0BA infants.\n                  <\/jats:p>","DOI":"10.1002\/jmv.29842","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T06:11:16Z","timestamp":1723097476000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Does cytomegalovirus infection and antiviral therapy affect prognosis of biliary atresia? A real\u2010world retrospective cohort study"],"prefix":"10.1002","volume":"96","author":[{"given":"Jie","family":"Dong","sequence":"first","affiliation":[{"name":"Pediatric Research Institute of Hunan Province, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanjuan","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renpeng","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bixiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chonggao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Fetal and Neonatal Surgery, The Affiliated Children's Hospital of Xiangya School of Medicine Central South University (Hunan Children's Hospital) Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22182"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathmechdis-031521-025623"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-022-00619-0"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.10.058"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.91"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60946-6"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)92970-X"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24807"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.11.035"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.12.014"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11040945"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-022-04093-4"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.03.001"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000175"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1668146"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50346"},{"key":"e_1_2_11_18_1","unstructured":"National Health Commission of the People's Republic of China. 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