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Among 93 cases, they had asymptomatic (<jats:italic>n<\/jats:italic>: 55) and symptomatic (<jats:italic>n<\/jats:italic>: 38). The median baseline blood viral load detected in the symptomatic cCMV (ScCMV) infection (13\u2009054 IU\/mL) was significantly higher than that of asymptomatic cCMV (AcCMV) infection (4636 IU\/mL) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.013). There was no difference in median viral clearance times (75 and 90 days, respectively) in baseline viremic cases in the ScCMV and AcCMV infection groups. There were no differences in median baseline blood viral load (6930 IU\/mL and 14\u2009268 IU\/mL, respectively) and median viral clearance times (75 and 85 days, respectively) between the 6\u2010week and 6\u2010month antiviral treatment group. No correlation was found between baseline blood viral load, clinical severity, and the number of systems involved. However, in initial viremic cases, the viral load threshold for a symptomatic case was 8856 IU\/mL, with 85.7% sensitivity and 54.5% specificity.<\/jats:p>","DOI":"10.1002\/jmv.29853","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T07:05:04Z","timestamp":1723532704000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of blood viral load in asymptomatic and symptomatic cases of congenital cytomegalovirus infection"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7121-3810","authenticated-orcid":false,"given":"\u00d6mer","family":"G\u00fcne\u015f","sequence":"first","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0839-1301","authenticated-orcid":false,"given":"Belgin","family":"G\u00fclhan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0677-7606","authenticated-orcid":false,"given":"Fatih","family":"\u00dc\u00e7karde\u015f","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Ad\u0131yaman University  Ad\u0131yaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3446-7034","authenticated-orcid":false,"given":"Ahmet Yasin","family":"G\u00fcney","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3111-6888","authenticated-orcid":false,"given":"Zehra Nihan","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8342-3786","authenticated-orcid":false,"given":"Seval","family":"\u00d6zen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2538-2872","authenticated-orcid":false,"given":"Saliha","family":"Kan\u0131k\u2010Y\u00fcksek","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5691-2461","authenticated-orcid":false,"given":"Asl\u0131nur","family":"\u00d6zkaya\u2010Parlakay","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases Ankara Bilkent City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1186\/s13052-017-0358-8"},{"issue":"10","key":"e_1_2_9_3_1","article-title":"A review of sensorineural hearing loss in congenital cytomegalovirus infection","volume":"14","author":"Singh G","year":"2022","journal-title":"Cureus"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1128\/CMR.00062-12"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.3109\/23744235.2015.1018316"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1093\/infdis\/jiu627"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1016\/S0022-3476(03)00192-6"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1056\/NEJMoa1404599"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1542\/peds.2005-0629"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1016\/j.jcv.2019.104231"},{"doi-asserted-by":"publisher","key":"e_1_2_9_11_1","DOI":"10.1093\/infdis\/jiy695"},{"doi-asserted-by":"publisher","key":"e_1_2_9_12_1","DOI":"10.17219\/acem\/125427"},{"doi-asserted-by":"publisher","key":"e_1_2_9_13_1","DOI":"10.1186\/1471-2431-3-13"},{"unstructured":"Demmler\u2010HarrisonGJ. 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