{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T21:57:22Z","timestamp":1775599042702,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009882","name":"Regione Lombardia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009882","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In line with European trends, since 2023 Lombardy (Northern Italy) is experiencing a resurgence of measles and an increased number of reported cases of fever and rash. Measles discarded cases observed in our region within the context of measles and rubella surveillance from the first few months of 2024 (\n                    <jats:italic>N\u2009<\/jats:italic>\n                    =\u200930) were investigated for parvovirus B19 (B19V) and other rash\u2010associated viruses. Thirteen cases tested positive for B19V DNA, representing a significant increase from previous years (on average 3 cases per year,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) and ~40% of all B19V DNA\u2010positive patients we detected since 2017. In 2024, B19V DNA\u2010positive subjects spanned all ages, and the virus was predominant among adolescents and adults (84.6%). Two B19V infected patients were hospitalised, and likely cross\u2010reacting anti\u2010measles virus IgM were found in both. Our data align with the recent reports from the ECDC and various European countries, which are experiencing a surge in B19V infections, and underline the importance of comprehensive measles and rubella surveillance systems that can adapt to changing epidemiological trends.\n                  <\/jats:p>","DOI":"10.1002\/jmv.29892","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T01:50:32Z","timestamp":1724982632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Differential diagnosis on measles and rubella discarded cases highlights a sharp increase in parvovirus B19 infections in Milan, Northern Italy, in the first months of 2024"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1573-5531","authenticated-orcid":false,"given":"Clara","family":"Fappani","sequence":"first","affiliation":[{"name":"Department of Health Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Coordinated Research Centre \u201cEpiSoMI\u201d Universit\u00e0 Degli Studi di Milano  Milan Italy"},{"name":"Department of Clinical Sciences and Community Health Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6478-2791","authenticated-orcid":false,"given":"Maria","family":"Gori","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Coordinated Research Centre \u201cEpiSoMI\u201d Universit\u00e0 Degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1365-9408","authenticated-orcid":false,"given":"Silvia","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Coordinated Research Centre \u201cEpiSoMI\u201d Universit\u00e0 Degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Senatore","sequence":"additional","affiliation":[{"name":"Health Protection Agency of the Metropolitan Area of Milan  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4079-1957","authenticated-orcid":false,"given":"Daniela","family":"Colzani","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marino","family":"Faccini","sequence":"additional","affiliation":[{"name":"Health Protection Agency of the Metropolitan Area of Milan  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5945-5710","authenticated-orcid":false,"given":"Danilo","family":"Cereda","sequence":"additional","affiliation":[{"name":"General Directorate of Welfare, Regione Lombardia  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6461-2231","authenticated-orcid":false,"given":"Luigi","family":"Vezzosi","sequence":"additional","affiliation":[{"name":"General Directorate of Welfare, Regione Lombardia  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9959-128X","authenticated-orcid":false,"given":"Marta","family":"Canuti","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Animal Sciences University of Copenhagen  Frederiksberg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0499-8977","authenticated-orcid":false,"given":"Antonella","family":"Amendola","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Universit\u00e0 degli Studi di Milano  Milan Italy"},{"name":"Coordinated Research Centre \u201cEpiSoMI\u201d Universit\u00e0 Degli Studi di Milano  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2024.29.16.2400201"},{"key":"e_1_2_10_3_1","unstructured":"World Health Organization.A 30\u2010Fold Rise of Measles Cases in 2023 in the WHO European Region Warrants Urgent Action Available online:https:\/\/www.who.int\/europe\/news\/item\/14-12-2023-a-30-fold-rise-of-measles-cases-in-2023-in-the-who-european-region-warrants-urgent-action(accessed on 6 June 2024)."},{"key":"e_1_2_10_4_1","unstructured":"European Centre for Disease Prevention and Control.Threat Assessment Brief: Measles on the Rise in the EU\/EEA \u2010 Considerations for Public Health Response Available online:https:\/\/www.ecdc.europa.eu\/en\/publications-data\/threat-assessment-brief-measles-rise-eueea-considerations-public-health-response(accessed on 6 June 2024)."},{"key":"e_1_2_10_5_1","unstructured":"World Health Organization. Joint Press Release from WHO and UNICEF: Measles Cases across Europe Continue to Surge Putting Millions of Children at Risk Available online:https:\/\/www.who.int\/europe\/news\/item\/28-05-2024-joint-press-release-from-who-and-unicef--measles-cases-across-europe-continue-to-surge--putting-millions-of-children-at-risk(accessed on 6 June 2024)."},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.29141"},{"key":"e_1_2_10_7_1","volume-title":"Manual for the Laboratory Diagnosis of Measles and Rubella Virus Infection","author":"World Health Organization"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28593"},{"key":"e_1_2_10_9_1","unstructured":"European Centre for Disease Prevention and Control.Communicable Disease Threats Report. April2024;14\u201320. Week 16 Av ailable online:https:\/\/www.ecdc.europa.eu\/en\/publications-data\/communicable-disease-threats-report-14-20-april-2024-week-16(accessed on 8 May 2024)."},{"key":"e_1_2_10_10_1","unstructured":"European Centre for Disease Prevention and Control.Risks Posed by Reported Increased Circulation of Human Parvovirus B19 in the EU\/EEA Available online:https:\/\/www.ecdc.europa.eu\/en\/publications-data\/risks-posed-reported-increased-circulation-human-parvovirus-b19-eueea(accessed on 6 June 2024)."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2024.29.21.2400253"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0000000000001263"},{"key":"e_1_2_10_13_1","unstructured":"World Health Organization.The Laboratory Confirmation of Suspected Measles Cases in Settings of Low Measles Transmission: Conclusions from the Experience in the Americas Available online:https:\/\/www.who.int\/publications-detail-redirect\/PMC2623064(accessed on 6 June 2024)."},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.01227-22"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.29892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T16:41:56Z","timestamp":1763224916000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.29892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/jmv.29892"],"URL":"https:\/\/doi.org\/10.1002\/jmv.29892","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,29]]},"assertion":[{"value":"2024-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e29892"}}