{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:15:12Z","timestamp":1792512912493,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    With the lifting of coronavirus disease 2019 (COVID\u201019) restrictions in December 2022 in China, the population was widely infected with COVID\u201019. We aim to analyzed changes in the epidemiological characteristics of other respiratory pathogens in children before and after the COVID\u201019 pandemic. We conducted a retrospective analysis of 44\u2009704 children with acute respiratory infections who underwent 11 respiratory pathogen tests based on multiplex polymerase chain reaction between February and December in both 2022 and 2023. The total pathogen detection rate (24861, 74.80% vs. 6423, 56.01%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000) and detection rates of coinfection (4059, 12.21% vs. 676, 5.89%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000) in 2023 was significantly higher than that in 2022. The detection rates of influenza A (2567, 7.72% vs. 222, 1.94%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), influenza B (383, 1.15% vs. 37, 0.32%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), human parainfluenza virus (2175, 6.54% vs. 602, 5.25%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), human metapneumovirus (1354, 4.07% vs. 346, 3.01%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), respiratory syncytial virus (3148, 9.47% vs. 870, 7.59%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000), and\n                    <jats:italic>Mycoplasma pneumonia<\/jats:italic>\n                    (MP; 9494, 28.56% vs. 1790, 15.61%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000) in 2023 were significantly higher than those in 2022, whereas the detection rates of human adenovirus (1124, 3.38% vs. 489, 4.26%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000) and human bocavirus (629, 1.89% vs. 375, 3.27%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.000) were significantly lower than those in 2022. Chlamydia, human rhinovirus, and human coronavirus showed similar detection rates between 2023 and 2022. In 2023, the influenza virus and human parainfluenza virus regained seasonal characteristic, an outbreak of MP infection occurred, the epidemic season of respiratory syncytial virus changed, and the proportion of children with acute respiratory infection aged 0\u201328 days and over 3 years old increased. Influenza B, metapneumovirus, and human bocavirus were detected in children aged 0\u201328 days in 2023, but not in 2022. After the COVID\u201019 pandemic, we should be alert to the increase of respiratory diseases and the change of epidemic season and susceptible age.\n                  <\/jats:p>","DOI":"10.1002\/jmv.29929","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T09:11:09Z","timestamp":1727082669000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Analyzing infections caused by 11 respiratory pathogens in children: Pre\u2010 and post\u2010COVID\u201019 pandemic trends in China"],"prefix":"10.1002","volume":"96","author":[{"given":"Huamei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine National Clinical Research Center For Child Health Hangzhou 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Clinical Research Center For Child Health Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31593-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2020.11.008"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.27334.1"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-022-07263-z"},{"issue":"3","key":"e_1_2_11_7_1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jinf.2022.12.030","article-title":"Changes of Mycoplasma pneumoniae prevalence in children before and after COVID\u201019 pandemic in Jenan, China","volume":"86","author":"Li X","year":"2023","journal-title":"J 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