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The study retrospectively analyzed the effects of IVIG administration on SFTS patients in both mild and severe groups. The primary outcome measure was 28\u2010day mortality. Inverse probability of treatment weighting (IPTW) with propensity score was used to account for baseline confounders. A total of SFTS patients with complete data enrolled from January 1, 2015, to August 1, 2023. Death at 28 days occurred for 68 (17.5%) patients. By unadjusted analysis, no difference was observed for 28\u2010day mortality between the IVIG and non\u2010IVIG groups in both the mild and severe groups. Similar results were found by propensity score matching and by IPTW analysis. Although IVIG is frequently used as adjuvant therapy for severe SFTS patients, no significant association was observed between IVIG treatment and reduced mortality in this patient population.<\/jats:p>","DOI":"10.1002\/jmv.70017","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T04:58:12Z","timestamp":1730696292000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Intravenous immunoglobulin\u2011based adjuvant therapy for severe fever with thrombocytopenia syndrome: A single\u2011center retrospective cohort study"],"prefix":"10.1002","volume":"96","author":[{"given":"Yu","family":"Zhai","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University Nanjing China"},{"name":"Department of Emergency Medicine Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University 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