{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T12:32:37Z","timestamp":1783859557514,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>While previous studies have primarily focused on post\u2010acute sequelae of COVID\u201019, the long\u2010term effects of SARS\u2010CoV\u20102 infection on alopecia areata (AA) among individuals with mental illness remain underexplored. Thus, this study aimed to address this gap by examining the association between post\u2010acute sequelae of COVID\u201019 and AA, with a specific focus on individuals with mental illness. This study utilized bi\u2010national, large\u2010scale, and population\u2010based cohorts of individuals with pre\u2010existing mental illness: a Korean nationwide cohort (K\u2010COV\u2010N cohort; main cohort; total <jats:italic>n<\/jats:italic>\u2009=\u20093\u2009248\u2009448) and a Japanese claims\u2010based cohort (JMDC cohort; replication cohort; total <jats:italic>n<\/jats:italic>\u2009=\u2009696\u2009332). The outcome focused on the new onset of AA following 30 days after SARS\u2010CoV\u20102 infection, defined using ICD\u201010 codes L63. Using a propensity score\u2010based overlap weighted algorithm, the adjusted hazard ratio (aHR)\u00a0for AA following COVID\u201019 was calculated for individuals with mental illness. In the main cohort, the risk of AA as post\u2010acute sequelae of COVID\u201019 was identified among individuals with mental illness (aHR, 1.32 [95% CI, 1.23\u20131.43]). The risk was significant for mild mental illness (aHR, 1.33 [95% CI, 1.24\u20131.44]) and within 6 months postinfection (aHR, 1.48 [95% CI, 1.35\u20131.63]). Similar findings were observed in the replication cohort. In conclusion, among individuals with mental illness, the risk of post\u2010acute sequelae of COVID\u201019 on AA\u00a0was elevated\u2014particularly in those with mild mental illness\u2014though this risk decreased over time. Our findings highlight the importance of early screening, integrated care, and equitable healthcare access for managing post\u2010acute sequelae of COVID\u201019.<\/jats:p>","DOI":"10.1002\/jmv.70364","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T01:05:19Z","timestamp":1745543119000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Post\u2010Acute Sequelae of COVID\u201019 on Alopecia Areata in Individuals With Mental Illness in South Korea and Japan: A Binational Population\u2010Based Cohort Study"],"prefix":"10.1002","volume":"97","author":[{"given":"Jaehyeong","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Medicine CHA University College of Medicine Seongnam South Korea"},{"name":"Center for Digital Health, Medical Science Research Institute Kyung Hee University College of Medicine Seoul South 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