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This systematic review and meta\u2010analysis aims to investigate the prevalence of HPV infection among Chinese males diagnosed with HPV\u2010related diseases. A systematic search was conducted across multiple electronic databases from inception to June 2023. Studies reporting the prevalence of HPV infection among Chinese males diagnosed with diseases potentially associated with HPV, without requiring sample type documentation, were included. Data extraction and quality assessment were performed independently by two reviewers. A random\u2010effects meta\u2010analysis was used to estimate the pooled prevalence of HPV infection. Among 105 studies on genital warts, the pooled prevalence was 81.25% for any HPV type, with 55.84% for low\u2010risk (LR) genotypes and 20.11% for high\u2010risk (HR) genotypes. Single infections (53.93%) were most common, with HPV 6 and 11 being the most prevalent. Among the LR genotypes, the prevalence was 73.76% for HPV 6 or 11. The most prevalent HR genotypes were HPV 16, 52, 58, 18, and 51. Among 102 studies on cancers, the prevalence was 10.83%, 28.97%, 28.14%, 19.50%, and 45.01% for oropharyngeal cancer, oral cancer, tonsil cancer, laryngeal cancer, and penile cancer, respectively. For anal cancer, one study reported 87.5% were HPV\u2010positive. This study highlights the prevalence of HPV genotypes 6, 11, 16, 18, 52, and 58 in males with genital warts, and the prevalence of HPV 16 and 18 in males with cancers in which HPV has been detected. Future investment in resources focused on male is needed.<\/jats:p>","DOI":"10.1002\/jmv.70469","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T06:03:59Z","timestamp":1752213839000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence of HPV Infection Among Chinese Males With HPV\u2010Related Diseases: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"97","author":[{"given":"Zexin","family":"Tao","sequence":"first","affiliation":[{"name":"Shandong Center for Disease Control and Prevention Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Immunization, Shanghai Municipal Center for Disease Control and Prevention Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoli","family":"Chen","sequence":"additional","affiliation":[{"name":"Value &amp; Implementation Global Medical &amp; Scientific Affairs, MSD China Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Value &amp; Implementation Global Medical &amp; Scientific Affairs, MSD China Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Bian","sequence":"additional","affiliation":[{"name":"Value &amp; Implementation Global Medical &amp; Scientific Affairs, MSD China Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Velicer","sequence":"additional","affiliation":[{"name":"Global Medical and Scientific Affairs, Merck &amp; Co. 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