{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:11:51Z","timestamp":1780063911644,"version":"3.54.0"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102), COVID\u201019 causative agent, infects several species. Although COVID\u201019 was reported in some dogs, their roles in transmitting SARS\u2010CoV\u20102 to other species remain unclear. We investigated the ability of COVID\u201019 infected dogs to transmit SARS\u2010CoV\u20102 virus to hamsters and assessed associated pulmonary and neuropathological changes in hamsters. SARS\u2010CoV\u20102\u2010negative hamsters were placed in close proximity to infected dogs, and viral infection in hamsters was confirmed by infection\u2010associated histopathological changes. SARS\u2010CoV\u20102 exposure led to notable neurological effects in hamsters, including blood\u2010brain barrier damage, activated immune response, and neurodegenerative changes. This study is the first one to confirm that dogs can transmit SARS\u2010CoV\u20102 to other species and demonstrates that cross\u2010species viral transmission can contribute to central nervous system pathology and promote neurodegenerative processes. These findings underscore the importance of further investigating dog\u2010to\u2010other species transmission pathways and early\u2010stage neuropathological impacts of SARS\u2010CoV\u20102 infection.<\/jats:p>","DOI":"10.1002\/jmv.70496","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T13:25:33Z","timestamp":1752758733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cross\u2010Species Transmission of SARS\u2010CoV\u20102 From Dogs to Hamsters and Pathological Changes in the Brain"],"prefix":"10.1002","volume":"97","author":[{"given":"Dong\u2010Hwi","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases College of Veterinary Medicine, Konkuk University Seoul Republic of Korea"},{"name":"Medicinal Materials Research Center, Biomedical Research Division Korea Institute of Science and Technology (KIST) Seoul Republic of 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