{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:15:04Z","timestamp":1769904904892,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>West Nile virus (WNV) infection poses significant diagnostic and clinical challenges in patients with hematologic malignancies. Herein, we present a retrospective case series of eight patients with lymphoma or multiple myeloma, hospitalized during the 2023\u20132024 WNV outbreaks in Israel. A confirmed neuroinvasive disease occurred in 50% and the mortality rate was 25%. Immunosuppressive therapies impaired serological diagnosis, necessitating PCR testing. This study underscores the need for heightened clinical suspicion, improved diagnostic strategies, and consideration of therapeutic interventions for WNV in immunocompromised hosts.<\/jats:p>","DOI":"10.1002\/jmv.70649","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:21:56Z","timestamp":1760613716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["West Nile Virus Infection in Hospitalized Patients With Lymphoma and Multiple Myeloma\u2014A Case Series Analysis"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3026-8724","authenticated-orcid":false,"given":"Yotam","family":"Bronstein","sequence":"first","affiliation":[{"name":"Department of Hematology Tel Aviv Sourasky Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yael C","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Hematology Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Faculty of Medical &amp; Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shai","family":"Levi","sequence":"additional","affiliation":[{"name":"Department of Hematology Tel Aviv Sourasky Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ora","family":"Halutz","sequence":"additional","affiliation":[{"name":"Clinical Microbiology Laboratory, Tel Aviv Sourasky Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hagin","sequence":"additional","affiliation":[{"name":"Faculty of Medical &amp; Health Sciences Tel Aviv University Tel Aviv Israel"},{"name":"Allergy and Clinical Immunology Unit, Tel\u2010Aviv Sourasky Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irit","family":"Avivi","sequence":"additional","affiliation":[{"name":"Department of Hematology Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Faculty of Medical &amp; Health Sciences Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/v6020606"},{"key":"e_1_2_7_3_1","unstructured":"European Centre for Disease Prevention and Control. Factsheet About West Nile Virus Infection [Internet] https:\/\/www.ecdc.europa.eu\/en\/west-nile-fever\/facts."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.4294"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000395"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.51894\/001c.5967"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4084\/mjhid.2019.033"},{"key":"e_1_2_7_8_1","unstructured":"Israeli Ministry of Health. West Nile Fever [Internet] https:\/\/www.gov.il\/en\/pages\/disease-west-nile-fever?chapterIndex=8."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20959"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102953"},{"key":"e_1_2_7_11_1","article-title":"West Nile Virus Outbreak in Israel 2024 Compared With Previous Seasons: A Retrospective Study","author":"Katzenellenbogen","year":"2025","journal-title":"Infectious Diseases and Therapy"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2015.1007043"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofv136"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac766"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1002799"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.280163"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1086\/376871"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.21.13350-13361.2005"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/427945"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.70649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.70649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.70649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T11:07:26Z","timestamp":1769857646000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.70649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/jmv.70649"],"URL":"https:\/\/doi.org\/10.1002\/jmv.70649","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70649"}}