{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T19:26:17Z","timestamp":1769541977156,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    To compare the repertoire of anti\u2010beta\u2010Coronavirus antibodies detected in dental pulp samples (systemic immunity) collected from individuals from the early 19th century previously investigated for dental calculus (local immunity) serological response, We investigated 10 dental pulp samples collected from 10 individuals excavated from a 1810\u20131813 military site in Charleville\u2010M\u00e9zi\u00e8res, France. The samples had previously been investigated for dental calculus serology. Dental pulp serology performed under a mini\u2010blot format, incorporated one positive and one negative control, and conjugated antibodies against the five classes of immunoglobulins. Dental pulp IgE serological response reliability was assessed by\n                    <jats:italic>in silico<\/jats:italic>\n                    analyses. Controls yielded expected results. Anti\u2010Coronavirus antibodies were detected in three individuals, comprising anti\u2010beta Coronavirus IgE in three individuals, IgG in two individuals, and IgA in one individual. IgA and IgG anti\u2010alpha Coronavirus were each detected in one individual. These results agreed with those previously obtained from the same 10 individuals with anti\u2010beta\u2010Coronavirus pooled IgG\/IgA\/IgM dental calculus paleoserology. Dental pulp paleoserology confirmed Coronavirus exposure in three individuals from the start of the 19th century in France. Translating these data into the modern medical literature, we propose that two centuries ago, some individuals suffered a yet unidentified beta\u2010Coronavirus infection.\n                  <\/jats:p>","DOI":"10.1002\/jmv.70800","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T09:16:12Z","timestamp":1768382172000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["IgE Anti\u2010Beta Coronaviruses Serology in Napoleon Soldiers, France"],"prefix":"10.1002","volume":"98","author":[{"given":"Nor El Houda","family":"Merrouche","sequence":"first","affiliation":[{"name":"IHU\u2010M\u00e9diterran\u00e9e Infection Marseille France"},{"name":"MEPHI Aix\u2010Marseille Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9rard","family":"Aboudharam","sequence":"additional","affiliation":[{"name":"IHU\u2010M\u00e9diterran\u00e9e Infection Marseille France"},{"name":"MEPHI Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"P\u00f4le Odontologie Assistance Publique \u2013 H\u00f4pitaux de Marseille Marseille France"},{"name":"\u00c9cole de M\u00e9decine Dentaire Aix\u2010Marseille\u2010Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandrine","family":"Thiol","sequence":"additional","affiliation":[{"name":"INRAP\/Centre Arch\u00e9ologique de Reims Universit\u00e9 de Reims Champagne\u2010 Ardenne Reims France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elodie","family":"Terrer","sequence":"additional","affiliation":[{"name":"IHU\u2010M\u00e9diterran\u00e9e Infection Marseille France"},{"name":"MEPHI Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"P\u00f4le Odontologie Assistance Publique \u2013 H\u00f4pitaux de Marseille Marseille France"},{"name":"\u00c9cole de M\u00e9decine Dentaire Aix\u2010Marseille\u2010Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Fantini","sequence":"additional","affiliation":[{"name":"INSERM UA 16 Aix Marseille Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Drancourt","sequence":"additional","affiliation":[{"name":"IHU\u2010M\u00e9diterran\u00e9e Infection Marseille France"},{"name":"MEPHI Aix\u2010Marseille Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamadou","family":"Oumarou Hama","sequence":"additional","affiliation":[{"name":"MEPHI Aix\u2010Marseille Universit\u00e9 Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"J.Hubert1854.Histoire de Charleville Depuis Son Origine Jusqu'en 1854. Charleville: Imprimerie de F. Hubert."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.24879"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1202"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.24138"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2023.03.019"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15091854"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2025.03.032"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.11.004"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacig.2023.100162"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-022-03382-y"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.14023"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-025-02677-y"},{"issue":"3","key":"e_1_2_9_14_1","first-page":"341","article-title":"Serum Immunoglobulin Levels as Potential Biomarkers of COVID\u201019 Pneumonia","volume":"53","author":"Nagarajan S.","year":"2023","journal-title":"Annals of Clinical and Laboratory Science"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.70800","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.70800","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.70800","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T05:39:10Z","timestamp":1769492350000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.70800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/jmv.70800"],"URL":"https:\/\/doi.org\/10.1002\/jmv.70800","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70800"}}