{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:01:14Z","timestamp":1792292474153,"version":"4.4.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Noroviruses are a major cause of acute gastroenteritis worldwide. In Beijing, norovirus GII.17 outbreaks, which dominated in 2014\u20132015 (66.7%), surged again from 1.3%\u201312.2% (2015\u20132024) to 81.7% (2024\u20132025), with reported outbreaks during July 2024\u2013February 2025 dramatically exceeding the prior year (301 vs. 103). From 2014 to 2025, 249 GII.17 outbreaks were identified, comprising 107 Kawasaki308 (1525 cases) and 142 Romania\u20102021 (1840 cases) based on phylogenetic analysis. The proportion of outbreak settings differed for Romania\u20102021 and Kawasaki308: kindergartens (35.2% vs. 37.4%), primary schools (46.5% vs. 29.0%), middle schools (5.6% vs. 12.1%) and others (12.7% vs. 21.5%). Romania\u20102021 cases were younger and had more vomiting than Kawasaki308 cases. Phylogenetic analysis revealed that novel GII.17 strains dominated in Beijing in 2024\u20132025 clustered with contemporaneous global strains, forming a distinct subcluster (New_2023\u20132025) within New (Romania\u20102021 like) cluster. This subcluster exhibited unique amino acid substitutions in VP1, VP2 and non\u2010structure proteins compared to other clusters and New subclusters. Our findings confirm the dominance of Romania\u20102021 like strains during 2024\u20132025 in Beijing. Differences in symptom profiles and affected age groups between Kawasaki308 and Romania\u20102021, and unique amino acid substitutions may help explain the rapid predominance of the emerging cluster.<\/jats:p>","DOI":"10.1002\/jmv.70803","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T18:01:12Z","timestamp":1768845672000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["GII.17[P17] Norovirus Resurge in Beijing, China, 2024\u20132025"],"prefix":"10.1002","volume":"98","author":[{"given":"Weihong","family":"Li","sequence":"first","affiliation":[{"name":"Beijing Key Laboratory of Surveillance Early Warning and Pathogen Research on Emerging Infectious Diseases, Beijing Center for Disease Prevention and Control Beijing China"},{"name":"School of Public Health Capital Medical University Beijing 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