{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T13:08:46Z","timestamp":1779368926680,"version":"3.53.0"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100005663","name":"Council of State and Territorial Epidemiologists","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Severe rhinovirus (RV)\/enterovirus (EV) respiratory infections in pediatric patients increased in the US during 2022\u20132023. This study aimed to characterize RV\/EV genetic diversity among hospitalized children in Wisconsin and describe demographic and clinical factors of patients by RV\/EV type. During September 2022\u2013April 2023, five Wisconsin pediatric hospitals submitted five RV\/EV\u2010positive specimens weekly to CDC. Viral typing was performed using partial viral protein (VP) 4\/VP2 (RV) and VP1 (EV) sequencing. Wisconsin Department of Health Services abstracted demographic, comorbid condition, and hospitalization course information from patient medical records. Ninety\u2010six patients were included in this investigation. RV\u2010C (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200940, 42%) and RV\u2010A (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200931, 32%) were the most frequently detected species, with 46 RV and 5 EV types identified. The median age was 2.5 (IQR: 0.7\u20135.5) years. Seventy\u2010one (74%) children had at least one comorbid condition. Asthma was more common among children with RV\u2010C infections (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200912, 30%) compared with other RVs (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20093, 9%) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02). RV\u2010A and RV\u2010C were important contributors to severe pediatric respiratory infection in Wisconsin. Molecular typing showed virus divergence typically observed during season\u2010long investigations. Year\u2010round molecular characterization is needed to better understand the contribution of RV\/EV types to severe pediatric respiratory illness.\n                  <\/jats:p>","DOI":"10.1002\/jmv.70879","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:27:16Z","timestamp":1774610836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diversity of Rhinovirus and Enterovirus Infections Among Pediatric Patients Hospitalized in Wisconsin, 2022\u20132023"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3874-7236","authenticated-orcid":false,"given":"Hannah L.","family":"Litwak","sequence":"first","affiliation":[{"name":"Wisconsin Division of Public Health Wisconsin Department of Health Services Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos M.","family":"Perez","sequence":"additional","affiliation":[{"name":"Wisconsin Division of Public Health Wisconsin Department of Health Services Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1094-3980","authenticated-orcid":false,"given":"Allen","family":"Bateman","sequence":"additional","affiliation":[{"name":"Wisconsin State Laboratory of Hygiene Madsion Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyley","family":"Anhalt","sequence":"additional","affiliation":[{"name":"Wisconsin State Laboratory of Hygiene Madsion Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Lu","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Rogers","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Emery","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4815-8697","authenticated-orcid":false,"given":"Terry Fei Fan","family":"Ng","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caelin","family":"Cubenas","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cria O.","family":"Gregory","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton","family":"Paden","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Haupt","sequence":"additional","affiliation":[{"name":"Wisconsin Division of Public Health Wisconsin Department of Health Services Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-3110","authenticated-orcid":false,"given":"Hannah L.","family":"Kirking","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah E.","family":"Segaloff","sequence":"additional","affiliation":[{"name":"Wisconsin Division of Public Health Wisconsin Department of Health Services Madison Wisconsin USA"},{"name":"Career Epidemiology Field Officer Program, US Centers for Disease Control and Prevention Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/v8010016"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piu099"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12020341"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11060521"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10040755"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy232"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000004127"},{"issue":"1","key":"e_1_2_10_9_1","first-page":"e151","article-title":"Genomic Epidemiology and Evolution of Rhinovirus in Western Washington State, 2021\u20132022","volume":"231","author":"Goya S.","year":"2025","journal-title":"Journal of Infectious 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